Sodium Glucose Cotransporter-2 Inhibitor Empagliflozin Reduces Infarct Size Independently of Sodium Glucose Cotransporter-2

被引：68

作者：

Chen, Sha ^{[1
]}

Wang, Qian ^{[1
]}

Christodoulou, Andriana ^{[4
]}

Mylonas, Nikolaos ^{[4
]}

Bakker, Diane ^{[1
]}

Nederlof, Rianne ^{[5
,6
]}

Hollmann, Markus W. ^{[1
]}

Weber, Nina C. ^{[1
]}

Coronel, Ruben ^{[2
]}

Wakker, Vincent ^{[3
]}

Christoffels, Vincent M. ^{[3
]}

Andreadou, Ioanna ^{[4
]}

Zuurbier, Coert J. ^{[1
]}

机构：

[1] Univ Amsterdam, Lab Expt Intens Care & Anesthesiol, Dept Anesthesiol, Amsterdam UMC,Amsterdam Cardiovasc Sci, Amsterdam, Netherlands

[2] Univ Amsterdam, Dept Expt Cardiol, Amsterdam UMC, Amsterdam Cardiovasc Sci, Amsterdam, Netherlands

[3] Univ Amsterdam, Dept Med Biol, Amsterdam UMC, Amsterdam Cardiovasc Sci, Amsterdam, Netherlands

[4] Natl & Kapodistrian Univ Athens, Pharmacol Lab, Fac Pharm, Athens, Greece

[5] Heinrich Heine Univ Dusseldorf, Med Fak, Inst Herz & Kreislaufphysiol, Dusseldorf, Germany

[6] Heinrich Heine Univ Dusseldorf, Univ Klinikum Dusseldorf, Dusseldorf, Germany

来源：

CIRCULATION | 2023年 / 147卷 / 03期

关键词：

body weight; empagliflozin; glucose; infarct size; ischemia; reperfusion; ketones; sodium-glucose cotransporter 2 inhibitor;

D O I：

10.1161/CIRCULATIONAHA.122.061688

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

[No abstract available]

引用

页码：276 / 279

页数：4

共 5 条

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[2] Direct cardiac effects of SGLT2 inhibitors [J].

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[3] Cardioprotection by selective SGLT-2 inhibitors in a non-diabetic mouse model of myocardial ischemia/reperfusion injury: a class or a drug effect? [J].

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[4] Infarct size, inflammatory burden, and admission hyperglycemia in diabetic patients with acute myocardial infarction treated with SGLT2-inhibitors: a multicenter international registry [J].

Paolisso, Pasquale ;

Bergamaschi, Luca ;

Santulli, Gaetano ;

Gallinoro, Emanuele ;

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Gragnano, Felice ;

Sardu, Celestino ;

Mileva, Niya ;

Foa, Alberto ;

Armillotta, Matteo ;

Sansonetti, Angelo ;

Amicone, Sara ;

Impellizzeri, Andrea ;

Casella, Gianni ;

Mauro, Ciro ;

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CARDIOVASCULAR DIABETOLOGY, 2022, 21 (01)

[5] Sodium Glucose Cotransporter-2 Inhibition for Acute Myocardial Infarction JACC Review Topic of the Week [J].

Udell, Jacob A. ;

Jones, W. Schuyler ;

Petrie, Mark C. ;

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Butler, Javed .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2022, 79 (20) :2058-2068

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