Palladium catalyzed remote-meta-C-H functionalization of aniline scaffolds

被引：1
|
作者：
Srinivas, Dasari [1 ]
Satyanarayana, Gedu [1 ]
机构：
[1] Indian Inst Technol IIT Hyderabad, Dept Chem, Kandi 502284, India
来源：
ORGANIC CHEMISTRY FRONTIERS | 2024年 / 11卷 / 05期
关键词：
ROOM-TEMPERATURE; BOND ACTIVATION; DIRECTING GROUP; OLEFINATION; ACID; ACETOXYLATION; ARYLATION; TEMPLATE;
D O I：
10.1039/d3qo01943h
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Here, we report on a microwave-assisted accelerated meta-C-H olefination of aniline derivatives using a simple aliphatic end-on nitrile assembly. Notably, the protocol shows broad substrate compatibility with remarkable regio-selectivity. It also showcases the removal of amide-based linkage and the template to furnish the meta-olefinated aniline derivative.
引用
收藏
页码：1473 / 1478
页数：6
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