Can the hemodynamic model in heart failure be restored based on analysis of ventricular-arterial coupling?

被引：0
|
作者：
Soma, Johannes [1 ]
机构：
[1] Cent Hosp Vestfold, Med Dept, Sect Cardiol, N-3103 Tonsberg, Norway
来源：
HEART FAILURE REVIEWS | 2024年 / 29卷 / 02期
关键词：
Heart Failure; Hemodynamics; Afterload; Pulse pressure; Vasodilation; Beta-blockade; HYPERTENSION; DYNAMICS;
D O I：
10.1007/s10741-023-10374-7
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The hemodynamic model was inappropriate to explain the disappointing effect of vasodilation and the beneficial effect of beta-blockade in chronic heart failure. A more nuanced hemodynamic analysis, taking both steady and pulsatile hemodynamics into consideration, improves insight into these apparently enigmatic effects. Of particular interest is the velocity of early systolic flow as a determinant of left ventricular afterload. Several drugs, in particular beta-blockers, directly or indirectly, influence the velocity of early systolic flow. Thus, the hemodynamic model in heart failure may deserve reconsideration.
引用
收藏
页码：463 / 464
页数：2
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