Gender Differences in Response to COVID-19 Infection and Vaccination

被引:13
作者
Zaher, Kawther [1 ,2 ]
Basingab, Fatemah [1 ,3 ]
Alrahimi, Jehan [1 ,3 ]
Basahel, Kholood [1 ,3 ]
Aldahlawi, Alia [1 ,3 ]
机构
[1] King Abdulaziz Univ, King Fahd Med Res Ctr, Immunol Unit, Jeddah 21859, Saudi Arabia
[2] King Abdulaziz Univ, Fac Appl Med Sci, Dept Med Lab Sci, Jeddah 21859, Saudi Arabia
[3] King Abdulaziz Univ, Fac Sci, Dept Biol Sci, Jeddah 21859, Saudi Arabia
关键词
coronavirus disease 2019 (COVID-19); severe acute respiratory syndrome; coronavirus 2 (SARS-CoV-2); sex hormones; pregnancy; RESPIRATORY SYNDROME CORONAVIRUS; X-CHROMOSOME INACTIVATION; IMMUNE-RESPONSE; SEX-DIFFERENCES; UNITED-STATES; ESTROGEN; WOMEN; TESTOSTERONE; EXPRESSION; PROTEIN;
D O I
10.3390/biomedicines11061677
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Since COVID-19 first appeared, a number of follow-up events have taken place. In an effort to find a solution to this catastrophe, a great deal of study and analysis has been conducted. Because of the high morbidity and exceptionally large losses, scientists are being pushed to conduct more research and find vaccination and treatments. The virus has a wide range of effects, one of which is how it affects sexual activity in both men and women. The impact of the cardiovascular system and susceptibility to embolism, lung stress, and infection heightens the probability of hospitalization in the intensive care unit for pregnant women who have contracted COVID-19. There is no evidence of infection being passed from mother to child. In the current review, the role of COVID-19 infection and vaccination on male and female sexual activity, hormones, and the menstrual cycle for females, as well as on male sex hormones and sexual activity during infection and after vaccination, are being investigated. There are no reports of the virus being isolated from the semen of an infected patient or recently recovered patients. A recent investigation on the influence of the virus on gender susceptibility to sexual organs and function has been uncovered throughout this study.
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页数:21
相关论文
共 137 条
[21]   Sex-Based Differences in Susceptibility to Severe Acute Respiratory Syndrome Coronavirus Infection [J].
Channappanavar, Rudragouda ;
Fett, Craig ;
Mack, Matthias ;
Ten Eyck, Patrick P. ;
Meyerholz, David K. ;
Perlman, Stanley .
JOURNAL OF IMMUNOLOGY, 2017, 198 (10) :4046-4053
[22]   Immune system and COVID-19 by sex differences and age [J].
Ciarambino, Tiziana ;
Para, Ombretta ;
Giordano, Mauro .
WOMENS HEALTH, 2021, 17
[23]   The Nucleocapsid Protein of Coronaviruses Acts as a Viral Suppressor of RNA Silencing in Mammalian Cells [J].
Cui, Lei ;
Wang, Haiying ;
Ji, Yanxi ;
Yang, Jie ;
Xu, Shan ;
Huang, Xingyu ;
Wang, Zidao ;
Qin, Lei ;
Tien, Po ;
Zhou, Xi ;
Guo, Deyin ;
Chen, Yu .
JOURNAL OF VIROLOGY, 2015, 89 (17) :9029-9043
[24]   Estrogens and autoimmune diseases [J].
Cutolo, Maurizio ;
Capellino, Silvia ;
Sulli, Alberto ;
Serioli, Bruno ;
Secchi, Maria Elena ;
Villaggio, Barbara ;
Straubb, Rawer H. .
ESTROGENS AND HUMAN DISEASES, 2006, 1089 :538-547
[25]  
Dhama K, 2020, CLIN MICROBIOL REV, V33, DOI [10.1128/CMR.00028-20, 10.1038/s41432-020-0088-4]
[26]   Coronavirus Diseases (COVID-19) Current Status and Future Perspectives: A Narrative Review [J].
Di Gennaro, Francesco ;
Pizzol, Damiano ;
Marotta, Claudia ;
Antunes, Mario ;
Racalbuto, Vincenzo ;
Veronese, Nicola ;
Smith, Lee .
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 2020, 17 (08)
[27]   Association Between Menstrual Cycle Length and Coronavirus Disease 2019 (COVID-19) Vaccination A US Cohort [J].
Edelman, Alison ;
Boniface, Emily R. ;
Benhar, Eleonora ;
Han, Leo ;
Matteson, Kristen A. ;
Favaro, Carlotta ;
Pearson, Jack T. ;
Darney, Blair G. .
OBSTETRICS AND GYNECOLOGY, 2022, 139 (04) :481-489
[28]   Assessment of Maternal and Neonatal SARS-CoV-2 Viral Load, Transplacental Antibody Transfer, and Placental Pathology in Pregnancies During the COVID-19 Pandemic [J].
Edlow, Andrea G. ;
Li, Jonathan Z. ;
Collier, Ai-ris Y. ;
Atyeo, Caroline ;
James, Kaitlyn E. ;
Boatin, Adeline A. ;
Gray, Kathryn J. ;
Bordt, Evan A. ;
Shook, Lydia L. ;
Yonker, Lael M. ;
Fasano, Alessio ;
Diouf, Khady ;
Croul, Natalie ;
Devane, Samantha ;
Yockey, Laura J. ;
Lima, Rosiane ;
Shui, Jessica ;
Matute, Juan D. ;
Lerou, Paul H. ;
Akinwunmi, Babatunde O. ;
Schmidt, Aaron ;
Feldman, Jared ;
Hauser, Blake M. ;
Caradonna, Timothy M. ;
de la Flor, Denis ;
D'Avino, Paolo ;
Regan, James ;
Corry, Heather ;
Coxen, Kendyll ;
Fajnzylber, Jesse ;
Pepin, David ;
Seaman, Michael S. ;
Barouch, Dan H. ;
Walker, Bruce D. ;
Yu, Xu G. ;
Kaimal, Anjali J. ;
Roberts, Drucilla J. ;
Alter, Galit .
JAMA NETWORK OPEN, 2020, 3 (12) :E2030455
[29]   SARS-CoV-2 Vaccine and Thrombosis: An Expert Consensus on Vaccine-Induced Immune Thrombotic Thrombocytopenia [J].
Elalamy, Ismail ;
Gerotziafas, Grigoris ;
Alamowitch, Sonia ;
Laroche, Jean-Pierre ;
Van Dreden, Patrick ;
Ageno, Walter ;
Beyer-Westendorf, Jan ;
Cohen, Alexander T. ;
Jimenez, David ;
Brenner, Benjamin ;
Middeldorp, Saskia ;
Cacoub, Patrice .
THROMBOSIS AND HAEMOSTASIS, 2021, 121 (08) :982-991
[30]   Data, disease and diplomacy: GISAID's innovative contribution to global health [J].
Elbe, Stefan ;
Buckland-Merrett, Gemma .
GLOBAL CHALLENGES, 2017, 1 (01) :33-46