ITGAL as a prognostic biomarker correlated with immune infiltrates in melanoma

被引：2
|
作者：
Deng, TengFei [1 ]
Wang, Chaoyong [2 ]
Gao, Cong [1 ]
Zhang, Qiang [1 ]
Guo, Jun [1 ]
机构：
[1] Yangzhou Univ, Plast Surg Dept, Affiliated Hosp, Yangzhou, Peoples R China
[2] Yangzhou Univ, Med Coll, Yangzhou, Peoples R China
来源：
FRONTIERS IN ONCOLOGY | 2023年 / 13卷
关键词：
ITGAL; melanoma; prognostic biomarker; immune infiltrates; MIHC; CELLS; ACTIVATION; ADHESION; CD4(+); CANCER; ICAM-1;
D O I：
10.3389/fonc.2023.1181537
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
This study investigates the relationship between ITGAL expression and immune infiltration, clinical prognosis, and specific types of T cells in melanoma tissue. The findings reveal the key role of ITGAL in melanoma and its potential mechanism of regulating tumor immune infiltrating cells, highlighting its potential as a diagnostic biomarker and therapeutic target for advanced melanoma.
引用
收藏
页数：14
相关论文
共 50 条
  • [21] PDGFRB is a potential prognostic biomarker and correlated with immune infiltrates in gastric cancer
    Liu, Baohong
    Xiao, Xingxing
    Lin, Ziqin
    Lou, Yongliang
    Zhao, Lingling
    CANCER BIOMARKERS, 2022, 34 (02) : 251 - 264
  • [22] GLIS1, Correlated with Immune Infiltrates, Is a Potential Prognostic Biomarker in Prostate Cancer
    Peng, Qiang
    Xie, Tingting
    Wang, Yuliang
    Ho, Vincy Wing-Sze
    Teoh, Jeremy Yuen-Chun
    Chiu, Peter Ka-Fung
    Ng, Chi-Fai
    Haendler, Bernard
    Tennstedt, Pierre
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2024, 25 (01)
  • [23] CDC6 is a prognostic biomarker and correlated with immune infiltrates in glioma
    Feng Wang
    Fen Zhao
    Li Zhang
    Lai Xiong
    Qing Mao
    Yanhui Liu
    Xiaoguang Qiu
    Xiang Wang
    Lin Shui
    Xi Chen
    Kexing Ren
    Pixian Shui
    Qiongwen Zhang
    Yifei Deng
    Weimin Li
    Xiaoqi Xie
    Dengbin Wu
    Tao Li
    Jinyi Lang
    Lei Liu
    Huaying Chen
    Jianguo Xu
    Sen Bai
    Zhiping Li
    Qiang Yue
    Ni Chen
    Bingwen Zhou
    Cheng Yi
    Yuquan Wei
    Yuchuan Fu
    Yong Luo
    Qiheng Gou
    Lunxu Liu
    Yuanzhao Liu
    Jingbo Kang
    Junjie Wang
    Dongcun Jing
    Fuquan Zhang
    Xiaoyan Yang
    Xianfeng Li
    Tao Jiang
    Zongcun Zhang
    Yizhi Zhou
    Junlin Yi
    Molecular Cancer, 21
  • [24] NFS1 as a Candidate Prognostic Biomarker for Gastric Cancer Correlated with Immune Infiltrates
    Jiang, You
    Li, Wenbo
    Zhang, Jun
    Liu, Kun
    Wu, Yuee
    Wang, Zhengguang
    INTERNATIONAL JOURNAL OF GENERAL MEDICINE, 2024, 17 : 3855 - 3868
  • [25] DIRAS2 Is a Prognostic Biomarker and Linked With Immune Infiltrates in Melanoma
    Xue, Wenli
    Zhu, Hongbo
    Liu, Hongye
    He, Hongxia
    FRONTIERS IN ONCOLOGY, 2022, 12
  • [26] LncRNA DIRC1 is a novel prognostic biomarker and correlated with immune infiltrates in stomach adenocarcinoma
    Lin, Yuning
    Zhang, Zhongying
    Li, Ying
    Chen, Yongquan
    Su, Meiying
    Zhao, Wenzhen
    MEDICINE, 2022, 101 (46) : E31839
  • [27] Phospholipase A/acyltransferase 4 is a prognostic biomarker and correlated with immune infiltrates in pancreatic cancer
    Li, Tian-Hao
    Wang, Yuan-Yang
    Zhao, Bang-Bo
    Qin, Cheng
    Li, Ze-Ru
    Wang, Wei-Bin
    HELIYON, 2022, 8 (09)
  • [28] LMNB2 is a prognostic biomarker and correlated with immune infiltrates in hepatocellular carcinoma
    Kong, Weihao
    Wu, Zihao
    Yang, Mingwei
    Zuo, Xiaomin
    Yin, Guanfu
    Chen, Wei
    IUBMB LIFE, 2020, 72 (12) : 2672 - 2685
  • [29] PTPRN Serves as a Prognostic Biomarker and Correlated with Immune Infiltrates in Low Grade Glioma
    Li, Peng
    Chen, Fanfan
    Yao, Chen
    Zhu, Kezhou
    Zhang, Bei
    Zheng, Zelong
    BRAIN SCIENCES, 2022, 12 (06)
  • [30] ARHGAP11A Is a Prognostic Biomarker and Correlated With Immune Infiltrates in Gastric Cancer
    Fan, Biao
    Ji, Ke
    Bu, Zhaode
    Zhang, Ji
    Yang, Heli
    Li, Jialin
    Wu, Xiaojiang
    FRONTIERS IN MOLECULAR BIOSCIENCES, 2021, 8
12345