Accommodation and vergence function in children using atropine combined with orthokeratology

被引:3
作者
Jiang, Jinyun [1 ]
Long, Wen [1 ]
Hu, Yin [1 ]
Zhao, Feng [1 ]
Zhao, Wenchen [1 ]
Zheng, Bingru [1 ]
Feng, Zhibin [1 ]
Li, Zhouyue [1 ,2 ]
Yang, Xiao [1 ,2 ]
机构
[1] Sun Yat Sen Univ, Zhongshan Opthalm Ctr, State Key Lab Ophthalmol, Guangzhou, Peoples R China
[2] Zhongshan Ophthalm Ctr, 54 S Xianlie Rd, Guangzhou 510060, Peoples R China
基金
中国国家自然科学基金;
关键词
Binocular vision; Myopia; Orthokeratology; Atropine; MYOPIA; METAANALYSIS; ONSET; LAG;
D O I
10.1016/j.clae.2022.101704
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Purpose: This study aimed to evaluate binocular vision in terms of vergence and accommodative measurements in children treated with 0.01% atropine combined with orthokeratology (OK).Methods: This was a prospective and randomized controlled clinical trial involving participants aged 8 to 12 years, with a spherical equivalent (SE) ranging from -1.00 to -6.00D. Participants were randomly divided into four groups: 1) a combination group using 0.01% atropine solution and OK lens; 2) an OK group using placebo solution and OK lens; 3) an atropine group using 0.01% atropine solution and wearing spectacles; and 4) a control group using placebo solution and wearing spectacles. Binocular vision was determined at baseline and at 3-month visits, with evaluations including horizontal phoria, fusional vergence, the accommodative conver-gence/accommodation (AC/A) ratio, accommodative lag, and accommodative amplitude (AA). The Wilcoxon signed-rank test was used to compare the changes in binocular vision in each group, and the Kruskal-Wallis test was used for comparisons of four groups.Results: Sixty-two participants completed the study. There was no significant difference in baseline refraction, accommodation or vergence measurements among the groups (all P > 0.05). Three months later, the accom-modative lag significantly decreased in the OK group (P = 0.002) but remained unchanged in the other three groups (all P > 0.05). In addition, binocular accommodative facilities and positive relative accommodations increased in the combination and OK groups (both P < 0.05) but remained unchanged in the atropine and control groups (both P > 0.05). Only the participants with esophoria in the OK group had a significant decrease in esophoria (P = 0.008). Moreover, the changes in fusional vergence and AC/A did not significantly differ between the four groups (all P > 0.05).Conclusion: Accommodative measurements changed similarly in the groups treated with OK. Changes in vergence measurements after treatment with 0.01% atropine were not significant.
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页数:6
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