Clinical Efficacy of Tapazole Integrated with Anti-Heart Failure Drugs in the Remedy of Hyperthyroidism Merged with Heart Failure

To observe the clinical efficacy and safety of tapazole integrated with anti-heart failure drugs in the remedy of hyperthyroidism merged with heart failure. Subjects (39-78) y suffering from hyperthyroidism and heart failure were enrolled, a total of 120 patients were divided into two subgroups according to different intervention methods, each of 60. Control subgroup was given anti-heart failure drugs, while the observation subgroup was given tapazole combined with anti-heart failure drugs. The clinical efficacy, thyroid functioning, cardiac functioning, immune functioning and adverse reactions of the two subgroups were compared. In terms of the total effective rate, vs. the observation subgroup (91.67 %) was notably higher than control subgroup (76.67 %). The concentrations of serum free triiodothyronine 3, free thyroxine 4 and n-terminal pro-brain natriuretic peptide in the observation subgroup were lower while thyroid stimulating hormone, left ventricular ejection fraction, stroke volume and ratio of mitral valve blood flow were higher. The increase of cluster of differentiation 3(+), cluster of differentiation 4(+) and cluster of differentiation 4(+)/cluster of differentiation 8(+) ratio in the observation subgroup was greater and cluster of differentiation 8(+) declined more notably. The remedy of hyperthyroidism and heart failure with tapazole combined with anti-heart failure drugs is more effective. It is safe and can improve the thyroid and heart functioning, thereby enhancing the body immunity.