Microbiome Dynamics: A Paradigm Shift in Combatting Infectious Diseases

被引:26
作者
Kamel, Mohamed [1 ]
Aleya, Sami [2 ]
Alsubih, Majed [3 ]
Aleya, Lotfi [4 ]
机构
[1] Cairo Univ, Fac Vet Med, Dept Med & Infect Dis, Giza 11221, Egypt
[2] Univ Bourgogne Franche Comte, Fac Med, F-25030 Besancon, France
[3] King Khalid Univ, Dept Civil Engn, Abha 62529, Saudi Arabia
[4] Univ Bourgogne Franche Comte, Lab Chrono Environm, CNRS, UMR 6249, F-25030 Besancon, France
关键词
infectious diseases; human microbiome; microbiome-targeted therapies; treatment approaches; host-pathogen interactions; GUT-BRAIN AXIS; IMMUNE-RESPONSES; SKIN MICROBIOME; VAGINAL MICROBIOME; COMMENSAL BACTERIA; HEALTH; IMPACT; RESISTANCE; DYSBIOSIS; METABOLITES;
D O I
10.3390/jpm14020217
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
Infectious diseases have long posed a significant threat to global health and require constant innovation in treatment approaches. However, recent groundbreaking research has shed light on a previously overlooked player in the pathogenesis of disease-the human microbiome. This review article addresses the intricate relationship between the microbiome and infectious diseases and unravels its role as a crucial mediator of host-pathogen interactions. We explore the remarkable potential of harnessing this dynamic ecosystem to develop innovative treatment strategies that could revolutionize the management of infectious diseases. By exploring the latest advances and emerging trends, this review aims to provide a new perspective on combating infectious diseases by targeting the microbiome.
引用
收藏
页数:50
相关论文
共 417 条
[1]   Exploring Relationships between Host Genome and Microbiome: New Insights from Genome-Wide Association Studies [J].
Abdul-Aziz, Muslihudeen A. ;
Cooper, Alan ;
Weyrich, Laura S. .
FRONTIERS IN MICROBIOLOGY, 2016, 7
[2]   Phage Therapy in the 21st Century: Is There Modern, Clinical Evidence of Phage-Mediated Efficacy? [J].
Abedon, Stephen T. ;
Danis-Wlodarczyk, Katarzyna M. ;
Alves, Diana R. .
PHARMACEUTICALS, 2021, 14 (11)
[3]   The Human Microbiome and Its Role in Musculoskeletal Disorders [J].
Aboushaala, Khaled ;
Wong, Arnold Y. L. ;
Barajas, Juan Nicolas ;
Lim, Perry ;
Al-Harthi, Lena ;
Chee, Ana ;
Forsyth, Christopher B. ;
Oh, Chun-do ;
Toro, Sheila J. ;
Williams, Frances M. K. ;
An, Howard S. ;
Samartzis, Dino .
GENES, 2023, 14 (10)
[4]   Effects of Antibiotic Treatment on Gut Microbiota and How to Overcome Its Negative Impacts on Human Health [J].
Acosta Ribeiro, Camila Fontoura ;
de Oliveira Silva Silveira, Gislaine Greice ;
Candido, Elizabete de Souza ;
Cardoso, Marlon Henrique ;
Espinola Carvalho, Cristiano Marcelo ;
Franco, Octavio Luiz .
ACS INFECTIOUS DISEASES, 2020, 6 (10) :2544-2559
[5]   The Potential of Antibiotics and Nanomaterial Combinations as Therapeutic Strategies in the Management of Multidrug-Resistant Infections: A Review [J].
Adeniji, Oluwaseun Ola ;
Nontongana, Nolonwabo ;
Okoh, Janet Chiyem ;
Okoh, Anthony Ifeanyi .
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 23 (23)
[6]   Metagenomics, Metatranscriptomics, and Metabolomics Approaches for Microbiome Analysis [J].
Aguiar-Pulido, Vanessa ;
Huang, Wenrui ;
Suarez-Ulloa, Victoria ;
Cickovski, Trevor ;
Mathee, Kalai ;
Narasimhan, Giri .
EVOLUTIONARY BIOINFORMATICS, 2016, 12 :5-16
[7]   Changes in the vaginal microbiota following antibiotic treatment forMycoplasma genitalium,Chlamydia trachomatisand bacterial vaginosis [J].
Ahrens, Peter ;
Andersen, Lee O'Brien ;
Lilje, Berit ;
Johannesen, Thor Bech ;
Dahl, Ebba Gomez ;
Baig, Sharmin ;
Jensen, Jorgen Skov ;
Falk, Lars .
PLOS ONE, 2020, 15 (07)
[8]   Innovative Approaches for Maintaining and Enhancing Skin Health and Managing Skin Diseases through Microbiome-Targeted Strategies [J].
AL-Smadi, Khadeejeh ;
Leite-Silva, Vania Rodrigues ;
Filho, Newton Andreo ;
Lopes, Patricia Santos ;
Mohammed, Yousuf .
ANTIBIOTICS-BASEL, 2023, 12 (12)
[9]   Role of gut microbiota in intestinal wound healing and barrier function [J].
Alam, Ashfaqul ;
Neish, Andrew .
TISSUE BARRIERS, 2018, 6 (03)
[10]   Emerging Technology-Driven Hybrid Models for Preventing and Monitoring Infectious Diseases: A Comprehensive Review and Conceptual Framework [J].
Albahlal, Bader M. .
DIAGNOSTICS, 2023, 13 (19)