Implementation and Assessment of a Laparotomy-Assisted Three-Port Fetoscopic Spina Bifida Repair Program

被引:2
作者
Keil, Corinna [1 ]
Koehler, Siegmund [1 ]
Sass, Benjamin [2 ]
Schulze, Maximilian [3 ]
Kalmus, Gerald [4 ]
Belfort, Michael [5 ,6 ]
Schmitt, Nicolas [4 ]
Diehl, Daniele [7 ]
King, Alice [6 ,8 ]
Gross, Stefanie [7 ]
Sutton, Caitlin D. [9 ]
Joyeux, Luc [6 ,8 ]
Wege, Mirjam [10 ]
Nimsky, Christopher [2 ]
Whitehead, Wiliam E. [6 ,11 ]
Uhl, Eberhard [12 ]
Huisman, Thierry A. G. M. [13 ]
Neubauer, Bernd A. [7 ]
Weber, Stefanie [14 ]
Hummler, Helmut [10 ]
Axt-Fliedner, Roland [15 ]
Bedei, Ivonne [15 ]
机构
[1] Philipps Univ, 1Department Prenatal Med & Fetal Therapy, D-35043 Marburg, Germany
[2] Philipps Univ, 2Department Neurosurg, D-35043 Marburg, Germany
[3] Philipps Univ, 3Department Neuroradiol, D-35043 Marburg, Germany
[4] Philipps Univ, 4Department Anesthesiol & Intens Care Med, D-35043 Marburg, Germany
[5] Texas Childrens Hosp, Baylor Coll Med, 5Department Obstet & Gynecol, Houston, TX 77030 USA
[6] Texas Childrens Hosp, Baylor Coll Med, Childrens Fetal Ctr 6Texas, Houston, TX 77030 USA
[7] Justus Liebig Univ Giessen, 7Department Pediat Neurol, D-35392 Giessen, Germany
[8] Texas Childrens Hosp, Baylor Coll Med, Dept Surg, 8Divis Pediat Surg, Houston, TX 77030 USA
[9] Texas Childrens Hosp, Baylor Coll Med, Perioperat, Pain Med, 9Department Pediat Anesthesiol, Houston, TX 77030 USA
[10] Univ Childrens Hosp Marburg, 10Divis Neonatol, D-35043 Marburg, Germany
[11] Texas Childrens Hosp, Baylor Coll Med, 11Department Neurosurg, Houston, TX 77030 USA
[12] Justus Liebig Univ, 12Department Neurosurg, D-35390 Giessen, Germany
[13] Texas Childrens Hosp, Baylor Coll Med, B Singleton Dept Radiol 13Edward, Houston, TX 77030 USA
[14] Univ Childrens Hosp Marburg, 14Divis Pediat Nephrol & Transplantat, D-35043 Marburg, Germany
[15] Justus Liebig Univ Giessen, 15Department Prenatal Med & Fetal Therapy, D-35390 Giessen, Germany
关键词
open spina bifida; fetal therapy; fetoscopic repair; standardized training; IN-UTERO; FETAL; MYELOMENINGOCELE; SURGERY; FETUSES; ANESTHESIA; LESION;
D O I
10.3390/jcm12155151
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Open spina bifida (OSB) is a congenital, non-lethal malformation with multifactorial etiology. Fetal therapy can be offered under certain conditions to parents after accurate prenatal diagnostic and interdisciplinary counseling. Since the advent of prenatal OSB surgery, various modifications of the original surgical techniques have evolved, including laparotomy-assisted fetoscopic repair. After a two-year preparation time, the team at the University of Giessen and Marburg (UKGM) became the first center to provide a three-port, three-layer fetoscopic repair of OSB via a laparotomy-assisted approach in the German-speaking area. We point out that under the guidance of experienced centers and by intensive multidisciplinary preparation and training, a previously described and applied technique could be transferred to a different setting.
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页数:12
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