Clinical efficacy of remdesivir for COVID-19 in children: A propensity-score-matched analysis

被引:3
作者
Shoji, Kensuke [1 ,6 ]
Asai, Yusuke [2 ,3 ]
Akiyama, Takayuki [2 ]
Tsuzuki, Shinya [2 ,3 ,4 ]
Matsunaga, Nobuaki [2 ]
Suzuki, Setsuko
Iwamoto, Noriko [3 ]
Funaki, Takanori [1 ]
Miyairi, Isao [1 ,5 ]
Ohmagari, Norio [2 ,3 ]
机构
[1] Natl Ctr Child Hlth & Dev, Dept Med Subspecialties, Div Infect Dis, Tokyo, Japan
[2] Natl Ctr Global Hlth & Med, AMR Clin Reference Ctr, Tokyo, Japan
[3] Natl Ctr Global Hlth & Med, Dis Control & Prevent Ctr, Dept Infect Dis, Tokyo, Japan
[4] Univ Antwerp, Fac Med & Hlth Sci, Antwerp, Belgium
[5] Hamamatsu Univ Sch Med, Dept Pediat, Hamamatsu, Shizuoka, Japan
[6] Natl Ctr Child Hlth & Dev, Dept Med Subspecialties, Div Infect Dis, 2-10-1 Okura,Setagaya Ku, Tokyo, Japan
关键词
Remdesivir; Children; Coronavirus disease 2019; Severe acute respiratory syndrome coronavirus; Defervescence;
D O I
10.1016/j.jiac.2023.06.006
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Clinical efficacy of remdesivir in children with COVID-19 is unclear. This propensity-score-matched retrospective cohort study of children with COVID-19 showed that the rate of patients achieving defervescence on Day 4 was higher in the remdesivir group than in the non-remdesivir group, but was not statistically different (86.7% vs 73.3%, P = 0.333).
引用
收藏
页码:930 / 933
页数:4
相关论文
共 50 条
  • [31] Clinical outcomes and considerations in outpatient with COVID-19 receiving remdesivir therapy
    Siami, Zeinab
    Rasooli, Aziz
    Zebardast, Jayran
    Jalali, Illahay
    Jamalimoghadamsiahkali, Saeidreza
    HEALTH SCIENCE REPORTS, 2024, 7 (07)
  • [32] The use of remdesivir outside of clinical trials during the COVID-19 pandemic
    Vesa Halimi
    Armond Daci
    Nevenka Ridova
    Irina Panovska-Stavridis
    Milena Stevanovic
    Venko Filipce
    Aleksandar Dimovski
    Aleksandra Grozdanova
    Journal of Pharmaceutical Policy and Practice, 13
  • [33] Clinical safety of remdesivir therapy in COVID-19 patients with renal insufficiency
    Park, Somi
    Kim, A. Reum
    Lee, Jiyoung
    Kang, Sung-Woon
    Sung, Heungsup
    Kim, Mi-Na
    Chang, Euijin
    Bae, Seongman
    Jung, Jiwon
    Kim, Min Jae
    Kim, Sung -Han
    Choi, Sang -Ho
    Kim, Yang Soo
    Song, Eun Hee
    Chong, Yong Pil
    JOURNAL OF INFECTION AND CHEMOTHERAPY, 2024, 30 (04) : 366 - 370
  • [34] The use of remdesivir outside of clinical trials during the COVID-19 pandemic
    Halimi, Vesa
    Daci, Armond
    Ridova, Nevenka
    Panovska-Stavridis, Irina
    Stevanovic, Milena
    Filipce, Venko
    Dimovski, Aleksandar
    Grozdanova, Aleksandra
    JOURNAL OF PHARMACEUTICAL POLICY AND PRACTICE, 2020, 13 (01)
  • [35] Effects of Remdesivir and Favipiravir on Covid-19 Clinical Outcomes : A Systematic Review and Meta-Analysis
    Nazari, Seyed Saeed Hashemi
    Karimi, Roya
    Mohammadian, Maryam
    Maghsoudi, Mohammadreza
    Khani, Yousef
    BIOMEDICAL RESEARCH AND THERAPY, 2023, 10 (05): : 5701 - 5716
  • [36] Real-world evidence of survival benefit of remdesivir: study of 419 propensity score-matched patients hospitalized over the alpha and delta waves of COVID-19 in New Orleans, LA
    Salvadori, Nicolas
    Fridman, Moshe
    Chiang, Mel
    Chen, Linda
    Wang, Chenyu
    Lee, Eunyoung
    Fonseca, Vivian
    Fusco, Dahlene N.
    Jourdain, Gonzague
    Drouin, Arnaud C.
    FRONTIERS IN MEDICINE, 2024, 11
  • [37] Clinical Outcomes and Survival Analysis of Remdesivir as a Treatment Option for Moderate to Severe COVID-19 Patients
    Aboelsaad, Iman
    Ashmawy, Rasha
    Mahrous, Doaa
    Sharaf, Sandy
    Aly, Shahinda
    Abdullatif, Sara
    Fakhry, Ayat
    Hassan, Basma
    Khamis, Dalia
    Aldakhs, Alaa
    Kamal, Ehab
    COVID, 2022, 2 (12): : 1758 - 1767
  • [38] Efficacy and Cardiovascular Safety of Remdesivir in COVID-19: A Case-Control Study
    Lakshmanan, Mageshwaran
    Chittaranjan, Vinothkumar
    Raju, Shanley-Abhishek
    Palanisamy, Priya Dharshini
    JOURNAL OF YOUNG PHARMACISTS, 2023, 15 (04) : 716 - 724
  • [39] Remdesivir in COVID-19: A critical review of pharmacology, pre-clinical and clinical studies
    Singh, Awadhesh Kumar
    Singh, Akriti
    Singh, Ritu
    Misra, Anoop
    DIABETES & METABOLIC SYNDROME-CLINICAL RESEARCH & REVIEWS, 2020, 14 (04) : 641 - 648
  • [40] Remdesivir for COVID-19: Why Not Dose Higher?
    Yan, Victoria C.
    Mueller, Florian L.
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2021, 65 (04)