Clinical efficacy of remdesivir for COVID-19 in children: A propensity-score-matched analysis

被引:3
作者
Shoji, Kensuke [1 ,6 ]
Asai, Yusuke [2 ,3 ]
Akiyama, Takayuki [2 ]
Tsuzuki, Shinya [2 ,3 ,4 ]
Matsunaga, Nobuaki [2 ]
Suzuki, Setsuko
Iwamoto, Noriko [3 ]
Funaki, Takanori [1 ]
Miyairi, Isao [1 ,5 ]
Ohmagari, Norio [2 ,3 ]
机构
[1] Natl Ctr Child Hlth & Dev, Dept Med Subspecialties, Div Infect Dis, Tokyo, Japan
[2] Natl Ctr Global Hlth & Med, AMR Clin Reference Ctr, Tokyo, Japan
[3] Natl Ctr Global Hlth & Med, Dis Control & Prevent Ctr, Dept Infect Dis, Tokyo, Japan
[4] Univ Antwerp, Fac Med & Hlth Sci, Antwerp, Belgium
[5] Hamamatsu Univ Sch Med, Dept Pediat, Hamamatsu, Shizuoka, Japan
[6] Natl Ctr Child Hlth & Dev, Dept Med Subspecialties, Div Infect Dis, 2-10-1 Okura,Setagaya Ku, Tokyo, Japan
关键词
Remdesivir; Children; Coronavirus disease 2019; Severe acute respiratory syndrome coronavirus; Defervescence;
D O I
10.1016/j.jiac.2023.06.006
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Clinical efficacy of remdesivir in children with COVID-19 is unclear. This propensity-score-matched retrospective cohort study of children with COVID-19 showed that the rate of patients achieving defervescence on Day 4 was higher in the remdesivir group than in the non-remdesivir group, but was not statistically different (86.7% vs 73.3%, P = 0.333).
引用
收藏
页码:930 / 933
页数:4
相关论文
共 50 条
  • [1] Propensity score matched analysis for the safety and effectiveness of remdesivir in COVID-19 patients with renal impairment
    Yang, Eunmi
    Choi, Han Zo
    Kim, Subin
    Oh, Dong Hyun
    Ahn, Mi Young
    Ham, Sinyoung
    Lee, Eunyoung
    Jeon, Jaehyun
    Kim, Min-Kyung
    Jang, Hee-Chang
    Park, Sang-Won
    Choi, Jae-Phil
    BMC INFECTIOUS DISEASES, 2024, 24 (01)
  • [2] Propensity score matched analysis for the safety and effectiveness of remdesivir in COVID-19 patients with renal impairment
    Eunmi Yang
    Han Zo Choi
    Subin Kim
    Dong Hyun Oh
    Mi Young Ahn
    Sinyoung Ham
    Eunyoung Lee
    Jaehyun Jeon
    Min-Kyung Kim
    Hee-Chang Jang
    Sang-Won Park
    Jae-Phil Choi
    BMC Infectious Diseases, 24
  • [3] A Propensity Score?Matched Observational Study of Remdesivir in Patients with COVID-19 and Severe Kidney Disease
    Seethapathy, Rituvanthikaa
    Zhao, Sophia
    Long, Joshua D.
    Strohbehn, Ian A.
    Sise, Meghan E.
    KIDNEY360, 2022, 3 (02): : 269 - 278
  • [4] Assessing the effect of remdesivir alone and in combination with corticosteroids on time to death in COVID-19: A propensity score-matched analysis
    Pourhoseingholi, Mohamad Amin
    Looha, Mehdi Azizmohammad
    Ilkhani, Saba
    Hatamabadi, Hamidreza
    Sadeghi, Amir
    Safavi-Naini, Seyed Amir Ahmad
    Heidari, Kamran
    Taraghikhah, Nazanin
    Fallah, Mohammad Mahdi
    Kalantar, Reyhaneh
    Naderi, Nariman
    Esbati, Romina
    Ebrahimi, Nastaran
    Solhpour, Ali
    Jamialahmadi, Tannaz
    Sahebkar, Amirhossein
    JOURNAL OF CLINICAL VIROLOGY PLUS, 2024, 4 (02):
  • [5] Compassionate use of remdesivir in children with COVID-19
    Mendez-Echevarria, Ana
    Perez-Martinez, Antonio
    Gonzalez del Valle, Luis
    Ara, Maria Fatima
    Melendo, Susana
    Ruiz de Valbuena, Marta
    Vazquez-Martinez, Jose Luis
    Morales-Martinez, Antonio
    Remesal, Agustin
    Sandor-Bajusz, Kinga Amalia
    Cabanas, Fernando
    Calvo, Cristina
    EUROPEAN JOURNAL OF PEDIATRICS, 2021, 180 (04) : 1317 - 1322
  • [6] Compassionate use of remdesivir in children with COVID-19
    Ana Méndez-Echevarría
    Antonio Pérez-Martínez
    Luis Gonzalez del Valle
    María Fátima Ara
    Susana Melendo
    Marta Ruiz de Valbuena
    Jose Luis Vazquez-Martinez
    Antonio Morales-Martínez
    Agustín Remesal
    Kinga Amália Sándor-Bajusz
    Fernando Cabañas
    Cristina Calvo
    European Journal of Pediatrics, 2021, 180 : 1317 - 1322
  • [7] Remdesivir in the Treatment of COVID-19: A Propensity Score-Matched Analysis from a Public Hospital in New York City Assessing Renal and Hepatic Safety
    Lim, Hyomin
    Palaiodimos, Leonidas
    Berto, Cesar G.
    Tedunjaiye, Oluwatitomi
    Malik, Paras
    Nagraj, Sanjana
    Choi, Hansol
    Seng, Nang San Hti Lar
    Kladas, Michail
    Kharawala, Amrin
    Karamanis, Dimitrios
    Varma, Nidhi
    Anjali, Acharya
    JOURNAL OF CLINICAL MEDICINE, 2022, 11 (11)
  • [8] Remdesivir versus Favipiravir in Hospitalized Patients with Moderate to Severe COVID-19 Pneumonia: A Propensity Score-Matched Retrospective Cohort Study
    Chavalertsakul, Karuna
    Sutherasan, Yuda
    Petnak, Tananchai
    Thammavaranucupt, Kanin
    Kirdlarp, Suppachok
    Boonsarngsuk, Viboon
    Sungkanuparph, Somnuek
    INTERNATIONAL JOURNAL OF GENERAL MEDICINE, 2024, 17 : 2163 - 2175
  • [9] Why Remdesivir Failed: Preclinical Assumptions Overestimate the Clinical Efficacy of Remdesivir for COVID-19 and Ebola
    Yan, Victoria C.
    Muller, Florian L.
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2021, 65 (10)
  • [10] Rapid Response to Remdesivir in Hospitalised COVID-19 Patients: A Propensity Score Weighted Multicentre Cohort Study
    Emiel Leegwater
    Lisa Dol
    Menno R. Benard
    Eveline E. Roelofsen
    Nathalie M. Delfos
    Machteld van der Feltz
    Femke P. N. Mollema
    Liesbeth B. E. Bosma
    Loes E. Visser
    Thomas H. Ottens
    Nathalie D. van Burgel
    Sesmu M. Arbous
    Lahssan H. El Bouazzaoui
    Rachel Knevel
    Rolf H. H. Groenwold
    Mark G. J. de Boer
    Leo G. Visser
    Frits R. Rosendaal
    Erik B. Wilms
    Cees van Nieuwkoop
    Infectious Diseases and Therapy, 2023, 12 : 2471 - 2484