The sensitivity of a string compression algorithm C asks how much the output size C(T) for an input string T can increase when a single character edit operation is performed on T. This notion enables one to measure the robustness of compression algorithms in terms of errors and/or dynamic changes occurring in the input string. In this paper, we analyze the worst-case multiplicative sensitivity of string compression algorithms, which is defined by maxTEEn{C(T')/C(T) : ed(T, T') = 1}, where ed(T, T') denotes the edit distance between T and T'. In particular, for the most common versions of the Lempel-Ziv 77 compressors, we prove that the worst-case multiplicative sensitivity is only a small constant (2 or 3, depending on the version of the Lempel-Ziv 77 and the edit operation type), i.e., the size of the Lempel-Ziv 77 factorizations can be larger by only a small constant factor. We strengthen our upper bound results by presenting matching lower bounds on the worst-case sensitivity for all these major versions of the Lempel-Ziv 77 factorizations. We generalize these results to the smallest bidirectional scheme b. In addition, we show that the sensitivity of a grammar-based compressor called GCIS (Grammar Compression by Induced Sorting) is also a small constant. Further, we extend the notion of the worst-case sensitivity to string repetitiveness measures such as the smallest string attractor size gamma and the substring complexity 8, and show that the worst-case sensitivity of 8 is also a small constant. These results contrast with the previously known related results such that the size z78 of the Lempel-Ziv 78 factorization can increase by a factor of S2(n1/4) (shown by Lagarde and Perifel), and the number r of runs in the Burrows-Wheeler transform can increase by a factor of S2(logn) (shown by Giuliani et al.) when a character is prepended to an input string of length n. By applying our sensitivity bounds of 8 or the smallest grammar to known results (cf. Navarro's survey) some non-trivial upper bounds for the sensitivities of important string compressors and repetitiveness measures including gamma, r, LZ-End, RePair, LongestMatch, and AVL-grammar, are derived. We also exhibit the worst-case additive sensitivity maxTEEn {C(T') -C(T) : ed(T, T') = 1}, which allows one to observe more details in the changes of the output sizes.(c) 2022 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).