High dietary and lifestyle inflammatory scores are associated with increased risk of chronic kidney disease in Iranian adults (vol 22, 1 , 2023)

被引：1

作者：

Farhadnejad, Hossein ^{[1
,2
]}

Teymoori, Farshad ^{[1
,3
]}

Jahromi, Mitra Kazemi ^{[4
]}

Mokhtari, Ebrahim ^{[1
]}

Asghari, Golaleh ^{[2
]}

Mirmiran, Parvin ^{[1
,2
]}

Azizi, Fereidoun ^{[5
]}

机构：

[1] Shahid Beheshti Univ Med Sci, Res Inst Endocrine Sci, Nutr & Endocrine Res Ctr, Tehran, Iran

[2] Shahid Beheshti Univ Med Sci, Natl Nutr & Food Technol Res Inst, Fac Nutr Sci & Food Technol, Dept Clin Nutr & Dietet, Tehran, Iran

[3] Univ Med Sci, Sch Publ Hlth, Dept Nutr, Tehran, Iran

[4] Hormozgan Univ Med Sci, Endocrinol & Metab Res Ctr, Bandar Abbas, Iran

[5] Shahid Beheshti Univ Med Sci, Res Inst Endocrine Sci, Endocrine Res Ctr, Tehran, Iran

来源：

NUTRITION JOURNAL | 2023年 / 22卷 / 01期

关键词：

Adults; Chronic kidney diseases; Dietary pattern; Inflammation; Lifestyle;

D O I：

10.1186/s12937-023-00839-8

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

Background: Systemic inflammation can be the initiator in developing chronic diseases that may be affected by the lifestyle and diet of individuals. In the current study, we aimed to assess the association of the inflammatory potential of diet and lifestyle, determined by the food-based index of dietary inflammatory potential (FBDI), dietary inflammation score (DIS), and lifestyle inflammation score (LIS), with risk of chronic kidney disease(CKD) in Iranian adults. Methods: A total of 6044 CKD-free individuals aged ≥ 18 years, were recruited from among participants of the Tehran Lipid and Glucose Study(surveys 3 and 4) and followed a mean of 6.03 years(follow-up rate:94.95%). Data on dietary intakes were determined using a food frequency questionnaire. The inflammatory potential of diet and lifestyle were determined based on three indices, including FBDI, DIS, and LIS. Using the National Kidney Foundation guidelines, we defined CKD as eGFR < 60 mL/min/1.73 m2. Results: Mean ± SD age of the study population(54.3% women) was 37.8 ± 12.8 years. We identified 1216(20.1%) new cases of CKD during the 6.03 years of follow-up (46,889.8 person-years). In the multivariable-adjusted model, the risk of CKD incident is increased across quartiles of FBDI (HR = 1.21;95%CI:1.03–1.42, Ptrend:0.014) and LIS (HR = 1.28;95%CI:1.07–1.55,Ptrend:0.006). However, no significant relationship was observed between the higher DIS score and CKD risk. Conclusion: Our findings showed that a higher inflammatory potential of diet and lifestyle, characterized by a higher score of FBDI and LIS, was related to increased incidence of CKD, while no significant relationship was reported between the DIS score and CKD incident. © 2023, The Author(s).

引用

页数：1