Exploring the Clinical Applications of Lemongrass Essential Oil: A Scoping Review

被引：2
作者：
Kusuma, Ikhwan Yuda [1 ,2 ]
Perdana, Muhammad Iqbal [3 ]
Vagvolgyi, Csaba [3 ]
Csupor, Dezso [2 ]
Tako, Miklos [3 ]
机构：
[1] Harapan Bangsa Univ, Fac Hlth, Pharm Study Program, Purwokerto 53182, Indonesia
[2] Univ Szeged, Inst Clin Pharm, Szikra Utca 8, H-6725 Szeged, Hungary
[3] Univ Szeged, Fac Sci & Informat, Dept Microbiol, Kozep Fasor 52, H-6726 Szeged, Hungary
来源：
PHARMACEUTICALS | 2024年 / 17卷 / 02期
关键词：
lemongrass; medicinal plant; essential oil; clinical application; therapy; databases of research publications; systematic literature search; PRISMA guidelines; CYMBOPOGON-CITRATUS; MEDICINAL-PLANTS; ANTIMICROBIAL ACTIVITY; EXTRACTION; FLEXUOSUS; STAPF; ANTIBACTERIAL; EFFICACY; CANDIDA;
D O I：
10.3390/ph17020159
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Lemongrass is a medicinal plant that produces essential oil with a variety of therapeutic properties. Although lemongrass essential oil (LGEO) is promising in clinical applications, the existing knowledge on the efficacy and safety of LGEO remains limited. This scoping review aimed to identify, summarize, and synthesize existing literature related to the clinical applications of LGEO to provide an overview of its potential therapeutic benefits for patients. Three databases (PubMed, Web of Science, Scopus) were used following the PRISMA-ScR guidelines to find articles published between 1 January 2013, and 1 November 2022. A total of 671 records were identified and 8 articles were included in this scoping review. The majority of patients received oromucosal and topical treatment. The results of the studies suggest that LGEO might be a useful tool in the treatment of periodontitis, gingivitis and oral malodour, with similar efficacy to chlorhexidine (anti-gingivitis effect) and doxycycline (periodontitis). Additionally, LGEO has the potential for treating pityriasis versicolor and preventing skin aging and may have anti-dandruff effects. These findings not only underscore the diverse clinical potential of LGEO but also emphasize its comparable efficacy to established treatments. Further research is imperative to comprehensively evaluate LGEO's effectiveness, safety, mechanisms of action, potential interactions with other medications, and its long-term tolerability across diverse populations.
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页数：13
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共 73 条
  • [1] Antimicrobial activity, cytotoxicity and chemical analysis of lemongrass essential oil (Cymbopogon flexuosus) and pure citral
    Adukwu, Emmanuel C.
    Bowles, Melissa
    Edwards-Jones, Valerie
    Bone, Heather
    [J]. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2016, 100 (22) : 9619 - 9627
  • [2] Akhila A., 2009, Essential oil-bearing grasses: the genus Cymbopogon
  • [3] Akula Sreekumar, 2021, Front Dent, V18, P32, DOI 10.18502/fid.v18i32.7237
  • [4] RIFM fragrance ingredient safety assessment, citral, CAS Registry Number 5392-40-5
    Api, A. M.
    Belmonte, F.
    Belsito, D.
    Biserta, S.
    Botelho, D.
    Bruze, M.
    Burton, G. A., Jr.
    Buschmann, J.
    Cancellieri, M. A.
    Dagli, M. L.
    Date, M.
    Dekant, W.
    Deodhar, C.
    Fryer, A. D.
    Gadhia, S.
    Jones, L.
    Joshi, K.
    Lapczynski, A.
    Lavelle, M.
    Liebler, D. C.
    Na, M.
    O'Brien, D.
    Patel, A.
    Penning, T. M.
    Ritacco, G.
    Rodriguez-Ropero, F.
    Romine, J.
    Sadekar, N.
    Salvito, D.
    Schultz, T. W.
    Siddiqi, F.
    Sipes, I. G.
    Sullivan, G.
    Thakkar, Y.
    Tokura, Y.
    Tsang, S.
    [J]. FOOD AND CHEMICAL TOXICOLOGY, 2020, 141
  • [5] Natural products in drug discovery: advances and opportunities
    Atanasov, Atanas G.
    Zotchev, Sergey B.
    Dirsch, Verena M.
    Supuran, Claudiu T.
    [J]. NATURE REVIEWS DRUG DISCOVERY, 2021, 20 (03) : 200 - 216
  • [6] Adjunctive use of essential oils following scaling and root planing - a randomized clinical trial
    Azad, Mohammad Fallah
    Schwiertz, Andreas
    Jentsch, Holger F. R.
    [J]. BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2016, 16
  • [7] GERANIOL INTERFERES WITH MEMBRANE FUNCTIONS IN STRAINS OF CANDIDA AND SACCHAROMYCES
    BARD, M
    ALBRECHT, MR
    GUPTA, N
    GUYNN, CJ
    STILLWELL, W
    [J]. LIPIDS, 1988, 23 (06) : 534 - 538
  • [8] Antioxidant status (CoQ10 and Vit. E levels) and immunohistochemical analysis of soft tissues in periodontal diseases
    Battino, Maurizio
    Bompadre, Stefano
    Politi, Alessia
    Fioroni, Massimiliano
    Rubini, Corrado
    Bullon, Pedro
    [J]. BIOFACTORS, 2005, 25 (1-4) : 213 - 217
  • [9] Evaluation of six plant species used traditionally in the treatment and control of diabetes mellitus in South Africa using in vitro methods
    Boaduo, N. K. K.
    Katerere, D.
    Eloff, J. N.
    Naidoo, V.
    [J]. PHARMACEUTICAL BIOLOGY, 2014, 52 (06) : 756 - 761
  • [10] Lemon grass (Cymbopogon citratus) essential oil as a potent anti-inflammatory and antifungal drugs
    Boukhatem, Mohamed Nadjib
    Ferhat, Mohamed Amine
    Kameli, Abdelkrim
    Saidi, Fairouz
    Kebir, Hadjer Tchoketch
    [J]. LIBYAN JOURNAL OF MEDICINE, 2014, 9
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