Alopecia areata. Diagnostic and therapeutic recommendations of the Polish Dermatological Society. Part 2: Treatment

被引:2
作者
Rakowska, Adriana [1 ]
Rudnicka, Lidia [1 ]
Olszewska, Malgorzata [1 ]
Bergler-Czop, Beata [2 ]
Czuwara, Joanna [1 ]
Brzezinska-Wcislo, Ligia [2 ]
Narbutt, Joanna [3 ]
Placek, Waldemar [4 ]
Zegarska, Barbara [5 ]
机构
[1] Med Univ Warsaw, Dept Dermatol, Warsaw, Poland
[2] Med Univ Silesia, Dept Dermatol, Katowice, Poland
[3] Med Univ Lodz, Dept Dermatol Pediat & Oncol Dermatol, Lodz, Poland
[4] Univ Warmia & Mazury, Dept Dermatol Sexually Transmitted Dis & Immunol, Olsztyn, Poland
[5] Nicolaus Copernicus Univ, Coll Med Bydgoszcz, Dept Cosmetol & Aesthet Dermatol, Torun, Poland
来源
PRZEGLAD DERMATOLOGICZNY | 2023年 / 110卷 / 02期
关键词
alopecia areata; baricitinib; biological treatment; contact immunotherapy; cyclosporine; deuruxolitinib; JAK inhibitors; methotrexate; glucocorticoids; ritlecitinib; treatment; triamcinolone acetonide; JANUS KINASE INHIBITORS; INTERNATIONAL EXPERT OPINION; SEVERE ATOPIC-DERMATITIS; TERM-FOLLOW-UP; TRIAMCINOLONE ACETONIDE; EFFICACY; METHOTREXATE; TOFACITINIB; SAFETY; CORTICOSTEROIDS;
D O I
10.5114/dr.2023.127811
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
The treatment goal in alopecia areata is induction of hair regrowth and halting the progression of the disease. Treatment decisions depend on the severity of the alopecia areata as assessed by the Severity of Alopecia Tool (SALT) or the Alopecia Areata Scale (AAS). In mild alopecia areata, very ultra-high potency topical glucocorticoids and intralesional triamcinolone acetonide are the mainstay of treatment. In moderate to severe alopecia areata, systemic treatment is usually required. Currently, the only drug dedicated for alopecia areata, approved in Europe and the United States is baricitinib. Ritlecitinib, a JAK3/TEC inhibitor is approved in the United States for individuals 12 years of age and older with severe alopecia areata and is expected to be approved in Europe soon. Other systemic medications used in alopecia areata include glucocorticoids, cyclosporine, and methotrexate. Contact immunotherapy may be considered. In alopecia areata, long-maintenance treatment is of substantial significance.
引用
收藏
页码:101 / 120
页数:20
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