Fibrillarin promotes homologous recombination repair by facilitating the recruitment of recombinase RAD51 to DNA damage sites

被引：0
作者：
Mu, Yanhua [1 ,2 ]
Han, Jinhua [3 ]
Wu, Mingjie [4 ]
Li, Zongfang [1 ]
Du, Ke [1 ]
Wei, Yameng [1 ]
Wu, Mengjie [5 ]
Huang, Jun [3 ,6 ,7 ]
机构：
[1] Xi An Jiao Tong Univ, Natl & Local Joint Engn Res Ctr Biodiagnosis & Bi, Affiliated Hosp 2, Xian 710004, Peoples R China
[2] Zhejiang Univ, Life Sci Inst, Ctr Cell Signaling Network, MOE Key Lab Biosyst Homeostasis & Protect & Innova, Hangzhou 310058, Peoples R China
[3] Zhejiang Hosp, Inst Zhejiang Prov, Dept Geriatr, Zhejiang Prov Key Lab Geriatr & Geriatr, Hangzhou 310030, Peoples R China
[4] Zhejiang Univ, Affiliated Hosp 1, Emergency & Trauma Ctr, Sch Med,Trauma Ctr, Hangzhou 310003, Peoples R China
[5] Zhejiang Univ, Affiliated Hosp Stomatol, Sch Stomatol, Key Lab Oral Biomed Res Zhejiang Prov,Sch Med, Hangzhou 310006, Peoples R China
[6] Zhejiang Univ, Life Sci Inst, Zhejiang Prov Key Lab Canc Mol Cell Biol, Hangzhou 310058, Peoples R China
[7] Zhejiang Univ, Sir Run Run Shaw Hosp, Sch Med, Dept Gen Surg, Hangzhou 310016, Peoples R China
来源：
JOURNAL OF ZHEJIANG UNIVERSITY-SCIENCE B | 2023年 / 24卷 / 12期
基金：
中国国家自然科学基金;
关键词：
DNA???; RAD51; RIBOSOMAL-RNA METHYLATION; SMALL NUCLEOLAR RNA; PROTEIN; DYNAMICS;
D O I：
10.1631/jzus.B2300518
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
??????(HR)????????DNA????(DSB)???????HR???????????RAD51??????DNA?????????,????????,???DNA?????,????DNA?????????,????(FBL)????HR?????????DNA??,FBL?????DSB??,????RAD51???????FBL???RAD51?DNA????????,HR?????????,????FBL??????????,?????DNA????????????FBL???RAD51?DNA???????????,????FBL???????????
引用
收藏
页码：1165 / 1173
页数：9
相关论文
共 22 条
  • [1] DEFECTIVE DNA-DEPENDENT PROTEIN-KINASE ACTIVITY IS LINKED TO V(D)J RECOMBINATION AND DNA-REPAIR DEFECTS ASSOCIATED WITH THE MURINE SCID MUTATION
    BLUNT, T
    FINNIE, NJ
    TACCIOLI, GE
    SMITH, GCM
    DEMENGEOT, J
    GOTTLIEB, TM
    MIZUTA, R
    VARGHESE, AJ
    ALT, FW
    JEGGO, PA
    JACKSON, SP
    [J]. CELL, 1995, 80 (05) : 813 - 823
  • [2] Genome Organization Drives Chromosome Fragility
    Canela, Andres
    Maman, Yaakov
    Jung, Seolkyoung
    Wong, Nancy
    Callen, Elsa
    Day, Amanda
    Kieffer-Kwon, Kyong-Rim
    Pekowska, Aleksandra
    Zhang, Hongliang
    Rao, Suhas S. P.
    Huang, Su-Chen
    Mckinnon, Peter J.
    Aplan, Peter D.
    Pommier, Yves
    Aiden, Erez Lieberman
    Casellas, Rafael
    Nussenzweig, Andre
    [J]. CELL, 2017, 170 (03) : 507 - +
  • [3] Hallmarks of Cancer: New Dimensions
    Hanahan, Douglas
    [J]. CANCER DISCOVERY, 2022, 12 (01) : 31 - 46
  • [4] DNA-DEPENDENT PROTEIN-KINASE CATALYTIC SUBUNIT - A RELATIVE OF PHOSPHATIDYLINOSITOL 3-KINASE AND THE ATAXIA-TELANGIECTASIA GENE-PRODUCT
    HARTLEY, KO
    GELL, D
    SMITH, GCM
    ZHANG, H
    DIVECHA, N
    CONNELLY, MA
    ADMON, A
    LEESMILLER, SP
    ANDERSON, CW
    JACKSON, SP
    [J]. CELL, 1995, 82 (05) : 849 - 856
  • [5] Direct imaging of human Rad51 nucleoprotein dynamics on individual DNA molecules
    Hilario, Jovencio
    Amitani, Ichiro
    Baskin, Ronald J.
    Kowalczykowski, Stephen C.
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2009, 106 (02) : 361 - 368
  • [6] Katsuki Y., 2020, GENOME INSTAB. DIS, V1, P155, DOI DOI 10.1007/S42764-020-00017-8
  • [7] Role of deubiquitinating enzymes in DNA double-strand break repair
    Li, Yunhui
    Yuan, Jian
    [J]. JOURNAL OF ZHEJIANG UNIVERSITY-SCIENCE B, 2021, 22 (01): : 63 - 72
  • [8] Protein dynamics of human RPA and RAD51 on ssDNA during assembly and disassembly of the RAD51 filament
    Ma, Chu Jian
    Gibb, Bryan
    Kwon, YoungHo
    Sung, Patrick
    Greene, Eric C.
    [J]. NUCLEIC ACIDS RESEARCH, 2017, 45 (02) : 749 - 761
  • [9] p53 Acts as a Safeguard of Translational Control by Regulating Fibrillarin and rRNA Methylation in Cancer
    Marcel, Virginie
    Ghayad, Sandra E.
    Belin, Stephane
    Therizols, Gabriel
    Morel, Anne-Pierre
    Solano-Gonzalez, Eduardo
    Vendrell, Julie A.
    Hacot, Sabine
    Mertani, Hichem C.
    Albaret, Marie Alexandra
    Bourdon, Jean-Christophe
    Jordan, Lee
    Thompson, Alastair
    Tafer, Yasmine
    Cong, Rong
    Bouvet, Philippe
    Saurin, Jean-Christophe
    Catez, Frederic
    Prats, Anne-Catherine
    Puisieux, Alain
    Diaz, Jean-Jacques
    [J]. CANCER CELL, 2013, 24 (03) : 318 - 330
  • [10] Real-time measurements of the nucleation, growth and dissociation of single Rad51-DNA nucleoprotein filaments
    Mine, Judith
    Disseau, Ludovic
    Takahashi, Masayuki
    Cappello, Giovanni
    Dutreix, Marie
    Viovy, Jean-Louis
    [J]. NUCLEIC ACIDS RESEARCH, 2007, 35 (21) : 7171 - 7187
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