Isolated Adrenal Metastases of Castration-Resistant Prostate Cancer

被引：4
作者：
Topal, Edanur [1 ,3 ]
Has Simsek, Duygu [1 ]
Vatansever, Sezai [2 ]
Sanli, Yasemin [1 ]
Kuyumcu, Serkan [1 ]
机构：
[1] Istanbul Univ, Istanbul Fac Med, Dept Nucl Med, Istanbul, Turkiye
[2] Istanbul Univ, Inst Oncol, Dept Med Oncol, Istanbul, Turkiye
[3] Istanbul Univ, Istanbul Fac Med, Dept Nucl Med, TR-34093 Istanbul, Turkiye
来源：
CLINICAL NUCLEAR MEDICINE | 2024年 / 49卷 / 01期
关键词：
adrenal metastases; prostate cancer; Ga-68-PSMA PET/CT; Lu-177-PSMA;
D O I：
10.1097/RLU.0000000000004964
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
We present isolated bilateral adrenal metastases successfully treated with Lu-177-PSMA in a 66-year-old man diagnosed with castration-resistant prostate cancer. The patient had progression under chemotherapy as depicted by Ga-68-PSMA PET/CT showing intense bilateral PSMA uptake in the adrenal masses, and metastasis-directed therapies were considered as the first option for improving survival because the patient was oligometastatic. However, surgery and radiotherapy were not justifiable options due to the high risk of definitive adrenal insufficiency; therefore, the patient received 4 cycles of Lu-177-PSMA treatment. Ga-68-PSMA PET/CT showed near-complete response in bilateral adrenal metastases, and no sign of adrenal insufficiency was observed during follow-up.
引用
收藏
页码：E8 / E9
页数：2
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