The Memory Orchestra: Contribution of Astrocytes

被引:14
作者
Chen, Yi-Hua [1 ]
Jin, Shi-Yang [1 ]
Yang, Jian-Ming [1 ]
Gao, Tian-Ming [1 ]
机构
[1] Southern Med Univ, Guangdong Hong Kong Macao Greater Bay Area Ctr Bra, Sch Basic Med Sci,Minist Educ,Guangdong Province K, Dept Neurobiol,State Key Lab Organ Failure Res,Key, Guangzhou 510515, Peoples R China
基金
中国国家自然科学基金;
关键词
Astrocytes; Learning and memory; GPCR; Calcium signal; Plasticity; ADENOSINE A(2A) RECEPTOR; SYNAPTIC PLASTICITY; NEUROTROPHIC FACTOR; LACTATE TRANSPORT; BRAIN METABOLISM; MODULATION; MICROGLIA; MOTOR; ACTIVATION; BDNF;
D O I
10.1007/s12264-023-01024-x
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
For decades, memory research has centered on the role of neurons, which do not function in isolation. However, astrocytes play important roles in regulating neuronal recruitment and function at the local and network levels, forming the basis for information processing as well as memory formation and storage. In this review, we discuss the role of astrocytes in memory functions and their cellular underpinnings at multiple time points. We summarize important breakthroughs and controversies in the field as well as potential avenues to further illuminate the role of astrocytes in memory processes.
引用
收藏
页码:409 / 424
页数:16
相关论文
共 124 条
[1]   Astrocytic Activation Generates De Novo Neuronal Potentiation and Memory Enhancement [J].
Adamsky, Adar ;
Kol, Adi ;
Kreisel, Tirzah ;
Doron, Adi ;
Ozeri-Engelhard, Nofar ;
Melcer, Talia ;
Refaeli, Ron ;
Horn, Henrike ;
Regev, Limor ;
Groysman, Maya ;
London, Michael ;
Goshen, Inbal .
CELL, 2018, 174 (01) :59-+
[2]   Microglia Enhance Synapse Activity to Promote Local Network Synchronization [J].
Akiyoshi, Ryohei ;
Wake, Hiroaki ;
Kato, Daisuke ;
Horiuchi, Hiroshi ;
Ono, Riho ;
Ikegami, Ako ;
Haruwaka, Koichiro ;
Omori, Toshiaki ;
Tachibana, Yoshihisa ;
Moorhouse, Andrew J. ;
Nabekura, Junichi .
ENEURO, 2018, 5 (05)
[3]   Cell Biology of Astrocyte-Synapse Interactions [J].
Allen, Nicola J. ;
Eroglu, Cagla .
NEURON, 2017, 96 (03) :697-708
[4]   Gliotransmitters Travel in Time and Space [J].
Araque, Alfonso ;
Carmignoto, Giorgio ;
Haydon, Philip G. ;
Oliet, Stephane H. R. ;
Robitaille, Richard ;
Volterra, Andrea .
NEURON, 2014, 81 (04) :728-739
[5]   Impermanence of dendritic spines in live adult CA1 hippocampus [J].
Attardo, Alessio ;
Fitzgerald, James E. ;
Schnitzer, Mark J. .
NATURE, 2015, 523 (7562) :592-+
[6]   Microglia roles in synaptic plasticity and myelination in homeostatic conditions and neurodevelopmental disorders [J].
Bar, Ela ;
Barak, Boaz .
GLIA, 2019, 67 (11) :2125-2141
[7]   Astrocyte deletion of Bmal1 alters daily locomotor activity and cognitive functions via GABA signalling [J].
Barca-Mayo, Olga ;
Pons-Espinal, Meritxell ;
Follert, Philipp ;
Armirotti, Andrea ;
Berdondini, Luca ;
Tonelli, Davide De Pietri .
NATURE COMMUNICATIONS, 2017, 8
[8]   Identification of region-specific astrocyte subtypes at single cell resolution [J].
Batiuk, Mykhailo Y. ;
Martirosyan, Araks ;
Wahis, Jerome ;
de Vin, Filip ;
Marneffe, Catherine ;
Kusserow, Carola ;
Koeppen, Jordan ;
Viana, Joao Filipe ;
Oliveira, Joao Filipe ;
Voet, Thierry ;
Ponting, Chris P. ;
Belgard, T. Grant ;
Holt, Matthew G. .
NATURE COMMUNICATIONS, 2020, 11 (01)
[9]   Astrocyte layers in the mammalian cerebral cortex revealed by a single-cell in situ transcriptomic map [J].
Bayraktar, Omer Ali ;
Bartels, Theresa ;
Holmqvist, Staffan ;
Kleshchevnikov, Vitalii ;
Martirosyan, Araks ;
Polioudakis, Damon ;
Ben Haim, Lucile ;
Young, Adam M. H. ;
Batiuk, Mykhailo Y. ;
Prakash, Kirti ;
Brown, Alexander ;
Roberts, Kenny ;
Paredes, Mercedes F. ;
Kawaguchi, Riki ;
Stockley, John H. ;
Sabeur, Khalida ;
Chang, Sandra M. ;
Huang, Eric ;
Hutchinson, Peter ;
Ullian, Erik M. ;
Hemberg, Martin ;
Coppola, Giovanni ;
Holt, Matthew G. ;
Geschwind, Daniel H. ;
Rowitch, David H. .
NATURE NEUROSCIENCE, 2020, 23 (04) :500-+
[10]   Astrocyte calcium signaling: the third wave [J].
Bazargani, Narges ;
Attwell, David .
NATURE NEUROSCIENCE, 2016, 19 (02) :182-189