Brief communication: body composition and hidden obesity in people living with HIV on antiretroviral therapy

被引:1
作者
Konishi, K. [1 ,2 ,3 ]
Nakagawa, H. [1 ]
Asaoka, T. [1 ]
Kasamatsu, Y. [1 ]
Goto, T.
Shirano, M. [1 ]
机构
[1] Osaka City Gen Hosp, Dept Infect Dis, Osaka, Japan
[2] Osaka Univ, Grad Sch Med, Dept Oral Microbial Control, 2-2 Yamadaoka, Suita, Osaka 5650871, Japan
[3] Osaka Univ Hosp, Dept Infect Control, Osaka, Japan
关键词
HIV; Antiretroviral therapy; Weight gain; Body composition; Japan; RISK;
D O I
10.1186/s12981-024-00599-3
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
BackgroundIncreased incidence of lifestyle diseases as side-effects of antiretroviral therapy (ART) have been reported in people living with HIV (PLWH). Few studies have evaluated obesity and hidden obesity in Japanese PLWH and their association with ART. In order to provide more appropriate drug selection and lifestyle guidance, we investigated the relationship between the effects of HIV infection and ART on the body composition of Japanese PLWH.MethodsPLWH who visited the outpatient clinic and had body composition measured using the body composition analyzer InBody 570 were included in this study. Medications, comorbidities, and blood test data were obtained. Body mass index (BMI), body fat percentage, and skeletal muscle mass index (SMI) were measured.ResultsIn this study, 543 patients were included. Based on body shape, patients were classified into a thin group (13), normal weight group (14), hidden obesity group (158), apparent obesity group (14), and obesity group (218). Compared with the normal weight group, the hidden obesity group had a higher prevalence of comorbidities and a lower SMI.ConclusionsPLWH are more likely to have obesity than the general population, indicating that hidden obesity is common even among those with a normal BMI. It is important to measure body fat percentage along with body weight, as hidden obesity can be missed. Further investigation of the effects of ART on body composition is needed.
引用
收藏
页数:5
相关论文
共 12 条
[1]  
[Anonymous], 2023, GUIDELINES USE ANTIR
[2]  
[Anonymous], 2000, J Jpn Soc Study Obes
[3]  
Japan Society for the Study of Obesity, 2016, Guidelines for the treatment of obesity
[4]   The Impact of Weight Gain During HIV Treatment on Risk of Pre-diabetes, Diabetes Mellitus, Cardiovascular Disease, and Mortality [J].
Kumar, Shejil ;
Samaras, Katherine .
FRONTIERS IN ENDOCRINOLOGY, 2018, 9
[5]  
Ministry of Health Labour and Welfare, 2019, NATL HLTH NUTR SURVE
[6]   Excessive Loss of Skeletal Muscle Mass in Older Adults With Type 2 Diabetes [J].
Park, Seok Won ;
Goodpaster, Bret H. ;
Lee, Jung Sun ;
Kuller, Lewis H. ;
Boudreau, Robert ;
de Rekeneire, Nathalie ;
Harris, Tamara B. ;
Kritchevsky, Stephen ;
Tylavsky, Frances A. ;
Nevitt, Michael ;
Cho, Yong-wook ;
Newman, Anne B. .
DIABETES CARE, 2009, 32 (11) :1993-1997
[7]  
Romero-Corral A, 2010, EUR HEART J, V31, P737, DOI [10.1093/eurheartj/ehn347, 10.1093/eurheartj/ehp487]
[8]   Weight Gain Following Initiation of Antiretroviral Therapy: Risk Factors in Randomized Comparative Clinical Trials [J].
Sax, Paul E. ;
Erlandson, Kristine M. ;
Lake, Jordan E. ;
Mccomsey, Grace A. ;
Orkin, Chloe ;
Esser, Stefan ;
Brown, Todd T. ;
Rockstroh, Jurgen K. ;
Wei, Xuelian ;
Carter, Christoph C. ;
Zhong, Lijie ;
Brainard, Diana M. ;
Melbourne, Kathleen ;
Das, Moupali ;
Stellbrink, Hans-Jurgen ;
Post, Frank A. ;
Waters, Laura ;
Koethe, John R. .
CLINICAL INFECTIOUS DISEASES, 2020, 71 (06) :1379-1389
[9]   Characteristics of Glucose Metabolism in Underweight Japanese Women [J].
Someya, Yuki ;
Tamura, Yoshifumi ;
Suzuki, Ruriko ;
Kaga, Hideyoshi ;
Kadowaki, Satoshi ;
Sugimoto, Daisuke ;
Kakehi, Saori ;
Funayama, Takashi ;
Furukawa, Yasuhiko ;
Takeno, Kageumi ;
Sato, Junko ;
Kanazawa, Akio ;
Kawamori, Ryuzo ;
Watada, Hirotaka .
JOURNAL OF THE ENDOCRINE SOCIETY, 2018, 2 (03) :279-289
[10]   Reduction of Skeletal Muscle, Especially in Lower Limbs, in Japanese Type 2 Diabetic Patients With Insulin Resistance and Cardiovascular Risk Factors [J].
Tajiri, Yuji ;
Kato, Tomoko ;
Nakayama, Hitomi ;
Yamada, Kentaro .
METABOLIC SYNDROME AND RELATED DISORDERS, 2010, 8 (02) :137-142