Three Patients With Chorea and Positive Voltage- Gated Potassium Channel Antibody: Is This the Link Between Hyperkinetic von Economo Disease and COVID-19?

被引：3

作者：

Dulanto, Jacqueline ^{[1
]}

Chu, David ^{[1
]}

Saffari, Pardis ^{[1
]}

Abdelshahid, Mina ^{[2
]}

Xu, Prissilla ^{[3
]}

Hauser, Jacob ^{[4
]}

Eskenazi, Jonathan ^{[5
]}

Morm, Lynnea ^{[2
]}

Liu, Antonio K. ^{[4
,5
,6
]}

机构：

[1] Internal Med, Adventist Hlth White Mem, Los Angeles, CA USA

[2] AltaMed Hlth Serv, Family Med, Los Angeles, CA USA

[3] Adventist Hlth White Mem, Pharm Serv, Los Angeles, CA USA

[4] Adventist Hlth White Mem, Neurology, Los Angeles, CA 90001 USA

[5] Calif Hosp Med Ctr, Neurol, Los Angeles, CA 90015 USA

[6] Loma Linda Univ, Sch Med, Neurol, Loma Linda, CA 92350 USA

来源：

CUREUS JOURNAL OF MEDICAL SCIENCE | 2023年 / 15卷 / 03期

关键词：

covid-19; voltage-gated potassium channel antibody; postinfectious; chorea; von economo disease; ACID;

D O I：

10.7759/cureus.35666

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Chorea, hemichorea, and other movement disorders have been reported after different pandemics since Constantin von Economo's time. In the current COVID-19 pandemic, numerous delayed neurological manifestations have been reported in the postinfectious or postvaccination periods. However, very few of these are movement disorders in nature; there are even fewer voltage-gated potassium channel (VGKC) antibody-related movement disorder cases in the literature. We encountered three patients with some COVID-19-related issues featuring both chorea and VGKC antibody. Modern medical science and technology may be able to further our understanding of the molecular basis of von Economo disease and reveal a possible link to COVID-19 along with the immunomodulation aspect of its treatment.

引用

页数：7

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