Efficacy of Antiviral Agents against Omicron Subvariants BQ.1.1 and XBB

被引：188

作者：

Imai, Masaki ^{[1
]}

Ito, Mutsumi ^{[1
]}

Kiso, Maki ^{[1
]}

Yamayoshi, Seiya ^{[1
]}

Uraki, Ryuta ^{[1
]}

Fukushi, Shuetsu ^{[2
]}

Watanabe, Shinji ^{[2
]}

Suzuki, Tadaki ^{[2
]}

Maeda, Ken ^{[2
]}

Sakai-Tagawa, Yuko ^{[1
]}

Iwatsuki-Horimoto, Kiyoko ^{[1
]}

Halfmann, Peter J. ^{[3
]}

Kawaoka, Yoshihiro ^{[1
]}

机构：

[1] Univ Tokyo, Tokyo, Japan

[2] Natl Inst Infect Dis, Tokyo, Japan

[3] Univ Wisconsin Madison, Madison, WI USA

来源：

NEW ENGLAND JOURNAL OF MEDICINE | 2023年 / 388卷 / 01期

关键词：

D O I：

10.1056/NEJMc2214302

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Antiviral Agents and Omicron BQ.1.1 and XBB Neither bebtelovimab nor any mAb combinations tested neutralized the SARS-CoV-2 omicron subvariants BQ.1.1 and XBB, but remdesivir, molnupiravir, and nirmatrelvir were efficacious against both in vitro.

引用

页码：89 / 91

页数：3

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