"Per protocol" practice patterns for Children's Oncology Group trials within the radiation oncology community

被引：1

作者：

Liu, Kevin X. ^{[1
]}

Hammoudeh, Lubna ^{[1
]}

Haas-Kogan, Daphne A. ^{[1
]}

Terezakis, Stephanie A. ^{[2
]}

机构：

[1] Harvard Med Sch, Brigham & Womens Hosp, Dana Farber Canc Inst, Dept Radiat Oncol,Boston Childrens Hosp, Boston, MA 02115 USA

[2] Univ Minnesota, Dept Radiat Oncol & Mol Radiat Sci, Minneapolis, MN 55455 USA

来源：

PEDIATRIC BLOOD & CANCER | 2023年 / 70卷 / 08期

关键词：

ependymoma; Ewing sarcoma; Hodgkin lymphoma; medulloblastoma; neuroblastoma; rhabdomyosarcoma; HIGH-RISK NEUROBLASTOMA; GROSS RESIDUAL DISEASE; PHASE-III TRIAL; HODGKIN LYMPHOMA; THERAPY; CHILDHOOD; CHEMOTHERAPY; RADIOTHERAPY; ESCALATION; PROGRAMS;

D O I：

10.1002/pbc.29673

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Little is known about the prevalence of pediatric radiation oncologists treating patients off study according to Children's Oncology Group (COG) trials before data are available regarding toxicity and efficacy of novel radiotherapy regimens. We conducted a 12-question survey of 358 pediatric radiation oncologists to characterize practice patterns regarding ongoing and completed COG protocols off study. With 130 responses (40.3%), the prevalence of providing treatment per protocol, but off study, before data are available in abstract or peer-reviewed form varied from 9.1% (for ACNS1422) to 88.1% (for AHOD1331). Future studies are needed to understand the effects of these practice patterns on outcomes.

引用

页数：5

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