Obstructive Uropathy with Uremia due to Advanced Cervical Cancer

PurposeCervical cancer is a worldwide public health problem because of its high mortality rate in women with a particularly high burden in many low-income and middle-income countries because of its advanced stage at diagnosis. The aim of our study was to analyze and provide evidence on survival and complications of ureteral stent placement or percutaneous nephrostomy treatment modalities in patients with obstructive uropathy and uremia caused by advanced cervical cancer.MethodsA retrospective observational study including patients diagnosed with obstructive uropathy due to advanced stage of cervical cancer. The patients were divided according to the type of interventional treatment they received as follows: the ureteral stent group and the percutaneous nephrostomy group. The primary outcome is survival rates compared between groups.ResultsA total of 28 patients were included, of whom the mean blood urea and creatinine was 86.76 +/- 60 mg/dL and 6.9 +/- 6.5 mg/dL, respectively. 53.3% of the patients underwent ureteral stenting and 46.4% required percutaneous nephrostomy. A total of 10 patients (35.7%) died, with an average survival of 6 (1-17) months.ConclusionPatients with advanced cervical cancer and obstructive uropathy who develop uremia due to renal involvement had a poor prognosis in the disease spectrum, with an average survival of 6 months despite comprehensive management.