MicroRNA targeting: A novel therapeutic intervention for ovarian cancer

被引：9

作者：

Asl, Elmira Roshani ^{[1
]}

Sarabandi, Sajed ^{[2
]}

Shademan, Behrouz ^{[3
]}

Dalvandi, Kourosh ^{[4
]}

Sheikhansari, Golshan ^{[5
]}

Nourazarian, Alireza ^{[6
]}

机构：

[1] Saveh Univ Med Sci, Social Determinants Hlth Res Ctr, Saveh, Iran

[2] Islamic Azad Univ Karaj, Fac Med Sci, Dept Vet, Karaj, Iran

[3] Tabriz Univ Med Sci, Stem Cell Res Ctr, Tabriz, Iran

[4] Minist Hlth & Med Educ, Hlth Dept, Tehran, Iran

[5] Tabriz Univ Med Sci, Student Res Comm, Tabriz, Iran

[6] Khoy Univ Med Sci, Dept Basic Med Sci, Khoy, Iran

来源：

BIOCHEMISTRY AND BIOPHYSICS REPORTS | 2023年 / 35卷

关键词：

Ovarian cancer; microRNA; Prognostics; Biomarker; Diagnostic biomarker; Therapeutic strategy; MESSENGER-RNAS; BREAST-CANCER; HEPATITIS-C; EXPRESSION; BIOMARKER; FAMILY; PROGRESSION; MECHANISMS; DIAGNOSIS; SEQUENCE;

D O I：

10.1016/j.bbrep.2023.101519

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Ovarian cancer, a perilous form of cancer affecting the female reproductive system, exhibits intricate communication networks that contribute to its progression. This study aims to identify crucial molecular abnormalities linked to the disease to enhance diagnostic and therapeutic strategies. In particular, we investigate the role of microRNAs (miRNAs) as diagnostic biomarkers and explore their potential in treating ovarian cancer. By targeting miRNAs, which can influence multiple pathways and genes, substantial therapeutic benefits can be attained. In this review we want to shed light on the promising application of miRNA-based interventions and provide insights into the specific miRNAs implicated in ovarian cancer pathogenesis.

引用

页数：8

共 102 条

[61]

Nagpal Madhav, 2016, Natl J Maxillofac Surg, V7, P17, DOI 10.4103/0975-5950.196135

[62] Clinicopathological features and treatment outcomes of metastatic tumors in the stomach [J].

Namikawa, Tsutomu ;

Hanazaki, Kazuhiro .

SURGERY TODAY, 2014, 44 (08) :1392-1399

[63]

Nana-Sinkam SP, 2010, IDRUGS, V13, P843

[64] New insights in the pathophysiology of ovarian cancer and implications for screening and prevention [J].

Nezhat, Farr R. ;

Apostol, Radu ;

Nezhat, Camran ;

Pejovic, Tanja .

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2015, 213 (03) :262-267

[65] MicroRNA: a new and promising potential biomarker for diagnosis and prognosis of ovarian cancer [J].

Pal, Manish K. ;

Jaiswar, Shyam P. ;

Dwivedi, Vinaya N. ;

Tripathi, Amit K. ;

Dwivedi, Ashish ;

Sankhwar, Pushplata .

CANCER BIOLOGY & MEDICINE, 2015, 12 (04) :328-341

[66] Antioxidant enzymes and lipid peroxidation in endometrium of patients with polyps, myoma, hyperplasia and adenocarcinoma [J].

Pejic, Snezana ;

Todorovic, Ana ;

Stojiljkovic, Vesna ;

Kasapovic, Jelena ;

Pajovic, Snezana B. .

REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY, 2009, 7

[67] The role of MicroRNAs in human cancer [J].

Peng, Yong ;

Croce, Carlo M. .

SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2016, 1

[68] Delivering the promise of miRNA cancer therapeutics [J].

Pereira, Diane M. ;

Rodrigues, Pedro M. ;

Borralho, Pedro M. ;

Rodrigues, Cecilia M. P. .

DRUG DISCOVERY TODAY, 2013, 18 (5-6) :282-289

[69] Small Drugs, Huge Impact: The Extraordinary Impact of Antisense Oligonucleotides in Research and Drug Development [J].

Quemener, Anais M. ;

Centomo, Maria Laura ;

Sax, Scott L. ;

Panella, Riccardo .

MOLECULES, 2022, 27 (02)

[70] Mutational analysis of cervical cytology improves diagnosis of endometrial cancer: A prospective multicentre cohort study [J].

Reijnen, Casper ;

van der Putten, Louis J. M. ;

Bulten, Johan ;

Snijders, Marc P. L. M. ;

Kusters-Vandevelde, Heidi V. N. ;

Sweegers, Sanne ;

Vos, Maria C. ;

van der Wurff, Anneke A. M. ;

Ligtenberg, Marjolijn J. L. ;

Massuger, Leon F. A. G. ;

Eijkelenboom, Astrid ;

Pijnenborg, Johanna M. A. .

INTERNATIONAL JOURNAL OF CANCER, 2020, 146 (09) :2628-2635

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