MicroRNA targeting: A novel therapeutic intervention for ovarian cancer

被引：9
作者：
Asl, Elmira Roshani [1 ]
Sarabandi, Sajed [2 ]
Shademan, Behrouz [3 ]
Dalvandi, Kourosh [4 ]
Sheikhansari, Golshan [5 ]
Nourazarian, Alireza [6 ]
机构：
[1] Saveh Univ Med Sci, Social Determinants Hlth Res Ctr, Saveh, Iran
[2] Islamic Azad Univ Karaj, Fac Med Sci, Dept Vet, Karaj, Iran
[3] Tabriz Univ Med Sci, Stem Cell Res Ctr, Tabriz, Iran
[4] Minist Hlth & Med Educ, Hlth Dept, Tehran, Iran
[5] Tabriz Univ Med Sci, Student Res Comm, Tabriz, Iran
[6] Khoy Univ Med Sci, Dept Basic Med Sci, Khoy, Iran
来源：
BIOCHEMISTRY AND BIOPHYSICS REPORTS | 2023年 / 35卷
关键词：
Ovarian cancer; microRNA; Prognostics; Biomarker; Diagnostic biomarker; Therapeutic strategy; MESSENGER-RNAS; BREAST-CANCER; HEPATITIS-C; EXPRESSION; BIOMARKER; FAMILY; PROGRESSION; MECHANISMS; DIAGNOSIS; SEQUENCE;
D O I：
10.1016/j.bbrep.2023.101519
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Ovarian cancer, a perilous form of cancer affecting the female reproductive system, exhibits intricate communication networks that contribute to its progression. This study aims to identify crucial molecular abnormalities linked to the disease to enhance diagnostic and therapeutic strategies. In particular, we investigate the role of microRNAs (miRNAs) as diagnostic biomarkers and explore their potential in treating ovarian cancer. By targeting miRNAs, which can influence multiple pathways and genes, substantial therapeutic benefits can be attained. In this review we want to shed light on the promising application of miRNA-based interventions and provide insights into the specific miRNAs implicated in ovarian cancer pathogenesis.
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页数：8
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