A rare case of pituitary metastasis from hepatocellular carcinoma: case report and literature review

被引:3
作者
Cheng, Yuanchen [1 ,2 ]
Feng, Ming [1 ]
机构
[1] Chinese Acad Med Sci & Peking Union Med Coll, Peking Union Med Coll Hosp, Dept Neurosurg, Beijing, Peoples R China
[2] Tsinghua Univ, Sch Med, Beijing, Peoples R China
关键词
pituitary; hepatocellular carcinoma; metastases; surgical treatment; pathology; GLAND; MIMICKING; DIAGNOSIS; TUMORS; PET;
D O I
10.3389/fonc.2023.1227678
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Presence of pituitary metastases (PMs) is a relatively rare clinical situation, especially when originating from hepatocellular carcinoma (HCC). A 73-year-old man presented with headaches, diplopia, and soon impaired vision, as well as gastrointestinal symptoms. Computed tomography (CT) and magnetic resonance imaging (MRI) of the brain revealed a space-occupying mass in the sellar region. The patient had a history of hepatocellular carcinoma and recent abdominal ultrasound and positron emission tomography (PET) indicated recurrence and metastases. Endoscopic transnasal transsphenoidal tumor excision was performed, and postoperative pathological report confirmed the diagnosis of HCC PM. In the literature review, 17 published cases of HCC PMs were summarized. Both the diagnosis and management of HCC PMs are difficult. Patients who had HCC-related history and new-onset headaches or diplopia should be inspected with a suspicion of metastatic lesions. Surgical intervention with transnasal endoscope is only recommended to ameliorate the symptoms and improve the life quality.
引用
收藏
页数:9
相关论文
共 37 条
[1]   Sellar and Parasellar Metastatic Tumors [J].
Altay, Tamer ;
Krisht, Khaled M. ;
Couldwell, William T. .
INTERNATIONAL JOURNAL OF SURGICAL ONCOLOGY, 2012, 2012
[2]   Rare case of hepatocellular carcinoma metastasising to the pituitary and cavernous sinus causing panhypopituitarism and bilateral ophthalmoplegia [J].
Ambalavanan, Jayachidambaram ;
Peravali, Monica ;
Perry, David J. .
BMJ CASE REPORTS, 2020, 13 (10)
[3]  
Aung T. H., 2002, Hong Kong Medical Journal, V8, P48
[4]  
Bray F, 2018, CA-CANCER J CLIN, V68, P394, DOI [10.3322/caac.21492, 10.3322/caac.21609]
[5]   Hepatocellular carcinoma presenting as nervous system involvement [J].
Chen, S. -F. ;
Tsai, N. -W. ;
Lui, C. -C. ;
Lu, C. -H. ;
Huang, C. -R. ;
Chuang, Y. -C. ;
Cheng, Y. -F. ;
Kuo, C. -H. ;
Chang, W. -N. .
EUROPEAN JOURNAL OF NEUROLOGY, 2007, 14 (04) :408-412
[6]  
CHIANA MF, 1990, NEUROCHIRURGIA, V33, P127
[7]   METASTASES FROM CARCINOMA OF MAMMARY-GLAND - AUTOPSY STUDY [J].
CIFUENTES, N ;
PICKREN, JW .
JOURNAL OF SURGICAL ONCOLOGY, 1979, 11 (03) :193-205
[8]   Multiple symptomatic vertebral artery loops treated with posterior cervical fusion [J].
Dandaleh, Nader S. ;
Albert, Gregory W. ;
Hasan, David M. .
JOURNAL OF CLINICAL NEUROSCIENCE, 2010, 17 (06) :788-790
[9]  
Fassett Daniel R, 2004, Neurosurg Focus, V16, pE8
[10]   Pituitary metastasis: is there still a place for neurosurgical treatment? [J].
Gilard, V. ;
Alexandru, C. ;
Proust, F. ;
Derrey, S. ;
Hannequin, P. ;
Langlois, O. .
JOURNAL OF NEURO-ONCOLOGY, 2016, 126 (02) :219-224