Several theories describe the increasing enlargement of the human brain because of environmental changes or dietary alterations. The environmental changes led to a change in diet quality (micronutrient density) because of changes in food foraging, which ensured that a growing brain was adequately supplied with energy and essential micronutrients for growth. The hippocampus is a direct link between nutrition and the environment, which is necessary for adapting to a changing climate. The adaptation then improves foraging success and enables better food quality and thus favors the development of the hippocampus, which in turn influences the development of other brain regions.The extraordinary ability of our ancestors for persistent running not only favored hunting but also had direct effects on hormones that support brain development. The connection between physical exercise, nutrition, and plasticity of the hippocampus and the resulting adaptation to changing environmental conditions is essential for triggering or stimulating brain development. As the variability selection hypothesis proposes, fluctuations in environmental conditions need a short adaptive answer, which may become genetically fixed and selected. The presented hypothesis allows a meaningful combination of the different theories of brain development (pulse climate, variability selection, amplifier lakes) and nutrition theories (aquatic, cooking, energy).The assumption that the hippocampus, as a "central sensory organ", detects new events and enables an adaptive response is not an isolated assumption for the hippocampus since other brain regions can also react similarly with synaptic plasticity. Through adult hippocampal neurogenesis (AHN), which is unique only in the hippocampus and synaptic plasticity, there is the possibility of detection and (neurological) storage of previously unknown events and linking them to other cortical areas, which may increase cortical volume.
机构:
Univ Minnesota, Sch Med, Grad Program Neurosci, Ctr Neurobehav Dev, Minneapolis, MN 55455 USA
Univ Minnesota, Sch Med, Med Scientist Training Program, Minneapolis, MN 55455 USAUniv Minnesota, Sch Med, Grad Program Neurosci, Ctr Neurobehav Dev, Minneapolis, MN 55455 USA
Carlson, Erik S.
Fretham, Stephanie J. B.
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机构:
Univ Minnesota, Sch Med, Grad Program Neurosci, Ctr Neurobehav Dev, Minneapolis, MN 55455 USAUniv Minnesota, Sch Med, Grad Program Neurosci, Ctr Neurobehav Dev, Minneapolis, MN 55455 USA
Fretham, Stephanie J. B.
Unger, Erica
论文数: 0引用数: 0
h-index: 0
机构:
Penn State Univ, Dept Nutr Sci, University Pk, PA 16802 USAUniv Minnesota, Sch Med, Grad Program Neurosci, Ctr Neurobehav Dev, Minneapolis, MN 55455 USA
Unger, Erica
O'Connor, Michael
论文数: 0引用数: 0
h-index: 0
机构:
Howard Hughes Med Inst, Chevy Chase, MD 20815 USAUniv Minnesota, Sch Med, Grad Program Neurosci, Ctr Neurobehav Dev, Minneapolis, MN 55455 USA
O'Connor, Michael
Petryk, Anna
论文数: 0引用数: 0
h-index: 0
机构:Univ Minnesota, Sch Med, Grad Program Neurosci, Ctr Neurobehav Dev, Minneapolis, MN 55455 USA
Petryk, Anna
Schallert, Timothy
论文数: 0引用数: 0
h-index: 0
机构:
Univ Texas Austin, Dept Psychol, Austin, TX 78746 USA
Univ Texas Austin, Dept Neurobiol, Austin, TX 78746 USA
Univ Michigan, Dept Neurosurg & Dev, Ann Arbor, MI 48109 USA
Univ Michigan, Ctr Human Growth & Dev, Ann Arbor, MI 48109 USAUniv Minnesota, Sch Med, Grad Program Neurosci, Ctr Neurobehav Dev, Minneapolis, MN 55455 USA
Schallert, Timothy
Rao, Raghavendra
论文数: 0引用数: 0
h-index: 0
机构:
Univ Minnesota, Sch Med, Grad Program Neurosci, Ctr Neurobehav Dev, Minneapolis, MN 55455 USA
Univ Minnesota, Sch Med, Grad Program Neurosci, Ctr Magnet Resonance Res, Minneapolis, MN 55455 USAUniv Minnesota, Sch Med, Grad Program Neurosci, Ctr Neurobehav Dev, Minneapolis, MN 55455 USA
Rao, Raghavendra
Tkac, Ivan
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h-index: 0
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Univ Minnesota, Sch Med, Grad Program Neurosci, Ctr Magnet Resonance Res, Minneapolis, MN 55455 USAUniv Minnesota, Sch Med, Grad Program Neurosci, Ctr Neurobehav Dev, Minneapolis, MN 55455 USA
Tkac, Ivan
Georgieff, Michael K.
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Univ Minnesota, Sch Med, Grad Program Neurosci, Ctr Neurobehav Dev, Minneapolis, MN 55455 USAUniv Minnesota, Sch Med, Grad Program Neurosci, Ctr Neurobehav Dev, Minneapolis, MN 55455 USA
机构:
Department of Reproductive Biology, MetroHealth Medical Center, 2500 MetroHealth Drive, Cleveland, 44109, OHDepartment of Reproductive Biology, MetroHealth Medical Center, 2500 MetroHealth Drive, Cleveland, 44109, OH
Catalano P.M.
Kirwan J.P.
论文数: 0引用数: 0
h-index: 0
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Department of Reproductive Biology, MetroHealth Medical Center, 2500 MetroHealth Drive, Cleveland, 44109, OHDepartment of Reproductive Biology, MetroHealth Medical Center, 2500 MetroHealth Drive, Cleveland, 44109, OH
机构:
Univ Utah, Dept Geol & Geophys, Salt Lake City, UT 84112 USAUniv Utah, Dept Geol & Geophys, Salt Lake City, UT 84112 USA
Cerling, Thure E.
Mbua, Emma
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h-index: 0
机构:
Natl Museums Kenya, Nairobi, KenyaUniv Utah, Dept Geol & Geophys, Salt Lake City, UT 84112 USA
Mbua, Emma
Kirera, Francis M.
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h-index: 0
机构:
Natl Museums Kenya, Nairobi, KenyaUniv Utah, Dept Geol & Geophys, Salt Lake City, UT 84112 USA
Kirera, Francis M.
Manthi, Fredrick Kyalo
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h-index: 0
机构:
Natl Museums Kenya, Nairobi, KenyaUniv Utah, Dept Geol & Geophys, Salt Lake City, UT 84112 USA
Manthi, Fredrick Kyalo
Grine, Frederick E.
论文数: 0引用数: 0
h-index: 0
机构:
SUNY Stony Brook, Dept Anthropol, Stony Brook, NY 11794 USAUniv Utah, Dept Geol & Geophys, Salt Lake City, UT 84112 USA
Grine, Frederick E.
Leakey, Meave G.
论文数: 0引用数: 0
h-index: 0
机构:
Natl Museums Kenya, Nairobi, Kenya
SUNY Stony Brook, Dept Anthropol, Stony Brook, NY 11794 USA
Turkana Basin Inst, Nairobi, KenyaUniv Utah, Dept Geol & Geophys, Salt Lake City, UT 84112 USA
Leakey, Meave G.
Sponheimer, Matt
论文数: 0引用数: 0
h-index: 0
机构:
Univ Colorado, Dept Anthropol, Boulder, CO 80309 USAUniv Utah, Dept Geol & Geophys, Salt Lake City, UT 84112 USA
Sponheimer, Matt
Uno, Kevin T.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Utah, Dept Geol & Geophys, Salt Lake City, UT 84112 USAUniv Utah, Dept Geol & Geophys, Salt Lake City, UT 84112 USA
机构:
Univ Minnesota, Sch Med, Grad Program Neurosci, Ctr Neurobehav Dev, Minneapolis, MN 55455 USA
Univ Minnesota, Sch Med, Med Scientist Training Program, Minneapolis, MN 55455 USAUniv Minnesota, Sch Med, Grad Program Neurosci, Ctr Neurobehav Dev, Minneapolis, MN 55455 USA
Carlson, Erik S.
Fretham, Stephanie J. B.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Minnesota, Sch Med, Grad Program Neurosci, Ctr Neurobehav Dev, Minneapolis, MN 55455 USAUniv Minnesota, Sch Med, Grad Program Neurosci, Ctr Neurobehav Dev, Minneapolis, MN 55455 USA
Fretham, Stephanie J. B.
Unger, Erica
论文数: 0引用数: 0
h-index: 0
机构:
Penn State Univ, Dept Nutr Sci, University Pk, PA 16802 USAUniv Minnesota, Sch Med, Grad Program Neurosci, Ctr Neurobehav Dev, Minneapolis, MN 55455 USA
Unger, Erica
O'Connor, Michael
论文数: 0引用数: 0
h-index: 0
机构:
Howard Hughes Med Inst, Chevy Chase, MD 20815 USAUniv Minnesota, Sch Med, Grad Program Neurosci, Ctr Neurobehav Dev, Minneapolis, MN 55455 USA
O'Connor, Michael
Petryk, Anna
论文数: 0引用数: 0
h-index: 0
机构:Univ Minnesota, Sch Med, Grad Program Neurosci, Ctr Neurobehav Dev, Minneapolis, MN 55455 USA
Petryk, Anna
Schallert, Timothy
论文数: 0引用数: 0
h-index: 0
机构:
Univ Texas Austin, Dept Psychol, Austin, TX 78746 USA
Univ Texas Austin, Dept Neurobiol, Austin, TX 78746 USA
Univ Michigan, Dept Neurosurg & Dev, Ann Arbor, MI 48109 USA
Univ Michigan, Ctr Human Growth & Dev, Ann Arbor, MI 48109 USAUniv Minnesota, Sch Med, Grad Program Neurosci, Ctr Neurobehav Dev, Minneapolis, MN 55455 USA
Schallert, Timothy
Rao, Raghavendra
论文数: 0引用数: 0
h-index: 0
机构:
Univ Minnesota, Sch Med, Grad Program Neurosci, Ctr Neurobehav Dev, Minneapolis, MN 55455 USA
Univ Minnesota, Sch Med, Grad Program Neurosci, Ctr Magnet Resonance Res, Minneapolis, MN 55455 USAUniv Minnesota, Sch Med, Grad Program Neurosci, Ctr Neurobehav Dev, Minneapolis, MN 55455 USA
Rao, Raghavendra
Tkac, Ivan
论文数: 0引用数: 0
h-index: 0
机构:
Univ Minnesota, Sch Med, Grad Program Neurosci, Ctr Magnet Resonance Res, Minneapolis, MN 55455 USAUniv Minnesota, Sch Med, Grad Program Neurosci, Ctr Neurobehav Dev, Minneapolis, MN 55455 USA
Tkac, Ivan
Georgieff, Michael K.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Minnesota, Sch Med, Grad Program Neurosci, Ctr Neurobehav Dev, Minneapolis, MN 55455 USAUniv Minnesota, Sch Med, Grad Program Neurosci, Ctr Neurobehav Dev, Minneapolis, MN 55455 USA
机构:
Department of Reproductive Biology, MetroHealth Medical Center, 2500 MetroHealth Drive, Cleveland, 44109, OHDepartment of Reproductive Biology, MetroHealth Medical Center, 2500 MetroHealth Drive, Cleveland, 44109, OH
Catalano P.M.
Kirwan J.P.
论文数: 0引用数: 0
h-index: 0
机构:
Department of Reproductive Biology, MetroHealth Medical Center, 2500 MetroHealth Drive, Cleveland, 44109, OHDepartment of Reproductive Biology, MetroHealth Medical Center, 2500 MetroHealth Drive, Cleveland, 44109, OH
机构:
Univ Utah, Dept Geol & Geophys, Salt Lake City, UT 84112 USAUniv Utah, Dept Geol & Geophys, Salt Lake City, UT 84112 USA
Cerling, Thure E.
Mbua, Emma
论文数: 0引用数: 0
h-index: 0
机构:
Natl Museums Kenya, Nairobi, KenyaUniv Utah, Dept Geol & Geophys, Salt Lake City, UT 84112 USA
Mbua, Emma
Kirera, Francis M.
论文数: 0引用数: 0
h-index: 0
机构:
Natl Museums Kenya, Nairobi, KenyaUniv Utah, Dept Geol & Geophys, Salt Lake City, UT 84112 USA
Kirera, Francis M.
Manthi, Fredrick Kyalo
论文数: 0引用数: 0
h-index: 0
机构:
Natl Museums Kenya, Nairobi, KenyaUniv Utah, Dept Geol & Geophys, Salt Lake City, UT 84112 USA
Manthi, Fredrick Kyalo
Grine, Frederick E.
论文数: 0引用数: 0
h-index: 0
机构:
SUNY Stony Brook, Dept Anthropol, Stony Brook, NY 11794 USAUniv Utah, Dept Geol & Geophys, Salt Lake City, UT 84112 USA
Grine, Frederick E.
Leakey, Meave G.
论文数: 0引用数: 0
h-index: 0
机构:
Natl Museums Kenya, Nairobi, Kenya
SUNY Stony Brook, Dept Anthropol, Stony Brook, NY 11794 USA
Turkana Basin Inst, Nairobi, KenyaUniv Utah, Dept Geol & Geophys, Salt Lake City, UT 84112 USA
Leakey, Meave G.
Sponheimer, Matt
论文数: 0引用数: 0
h-index: 0
机构:
Univ Colorado, Dept Anthropol, Boulder, CO 80309 USAUniv Utah, Dept Geol & Geophys, Salt Lake City, UT 84112 USA
Sponheimer, Matt
Uno, Kevin T.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Utah, Dept Geol & Geophys, Salt Lake City, UT 84112 USAUniv Utah, Dept Geol & Geophys, Salt Lake City, UT 84112 USA