Non-engineered T cells with specific anticancer effects in KRAS-mutated colorectal cancer

被引:0
|
作者
Lim, Sunki [1 ]
Gho, Yujeong [1 ]
Kim, Seoyoung [1 ]
Kim, Min Ki [1 ]
Park, Jong Seob [1 ]
Lee, Wang Jun [1 ]
Lee, Young-Kwan [1 ]
Moon, Hyoun Jong [1 ]
机构
[1] Excelsisbio Inc, Goyang, South Korea
关键词
D O I
10.1158/1538-7445.AM2023-3200
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
3200
引用
收藏
页数:2
相关论文
共 50 条
  • [41] Response to comment on 'KRAS-mutated plasma DNA as predictor of outcome from irinotecan monotherapy in metastatic colorectal cancer'
    Spindler, K-L G.
    Pallisgaard, N.
    Andersen, R. F.
    Jakobsen, A.
    BRITISH JOURNAL OF CANCER, 2014, 111 (12) : 2380 - 2380
  • [42] Lasting response by vertical inhibition with cetuximab and trametinib in KRAS-mutated colorectal cancer patient-derived xenografts
    Reissig, Timm M.
    Ladigan-Badura, Swetlana
    Steinberg, Anja
    Maghnouj, Abdelouahid
    Li, Ting
    Verdoodt, Berlinda
    Liffers, Sven T.
    Pohl, Michael
    Wolters, Heiner
    Teschendorf, Christian
    Viebahn, Richard
    Admard, Jakob
    Casadei, Nicolas
    Tannapfel, Andrea
    Schmiegel, Wolff
    Hahn, Stephan A.
    Vangala, Deepak B.
    MOLECULAR ONCOLOGY, 2023, 17 (11) : 2396 - 2414
  • [43] A Phase II Study of Sorafenib Combined With Cetuximab in EGFR-Expressing, KRAS-Mutated Metastatic Colorectal Cancer
    Do, Khanh
    Cao, Liang
    Kang, Zhigang
    Turkbey, Baris
    Lindenberg, Maria L.
    Larkins, Erin
    Holkova, Beata
    Steinberg, Seth M.
    Raffeld, Mark
    Peer, Cody J.
    Figg, William D.
    Eugeni, Michelle
    Jacobs, Paula
    Choyke, Peter
    Wright, John J.
    Doroshow, James H.
    Kummar, Shivaani
    CLINICAL COLORECTAL CANCER, 2015, 14 (03) : 154 - 161
  • [44] Engineered T cells for Colorectal Cancer
    Bakarurraini, Nurul Ainaa Adilah Rus
    Kamarudin, Ammar Akram
    Jamal, Rahman
    Abu, Nadiah
    IMMUNOTHERAPY, 2024, 16 (14-15) : 987 - 998
  • [45] p27kip1 expression and phosphorylation dictate Palbociclib sensitivity in KRAS-mutated colorectal cancer
    Vinciguerra, Gian Luca Rampioni
    Dall'Acqua, Alessandra
    Segatto, Ilenia
    Mattevi, Maria Chiara
    Russo, Francesca
    Favero, Andrea
    Cirombella, Roberto
    Mungo, Giorgia
    Viotto, Davide
    Karimbayli, Javad
    Pesce, Margherita
    Vecchione, Andrea
    Belletti, Barbara
    Baldassarre, Gustavo
    CELL DEATH & DISEASE, 2021, 12 (10)
  • [46] Alisertib exerts KRAS allele-specific anticancer effects on colorectal cancer cell lines
    Ren, Baojun
    Geng, Yan
    Chen, Shuxiang
    Gao, Zhuowei
    Zheng, Kehong
    Yang, Yong
    Luo, Qimei
    Feng, Jing
    Luo, Zhentao
    Ju, Yongle
    Huang, Zonghai
    EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2023, 25 (06)
  • [47] Stratification of patients with KRAS-mutated advanced non-small cell lung cancer: improving prognostics
    Zhang, Yuda
    Zeng, Fanxu
    Peng, Shixuan
    Chen, Yangqian
    Jiang, Wenjuan
    Wang, Zhan
    Deng, Li
    Huang, Zhe
    Qin, Haoyue
    Yan, Huan
    Zhang, Xing
    Zhang, Lin
    Yang, Nong
    Gong, Qian
    Zeng, Liang
    Zhang, Yongchang
    EXPERT REVIEW OF RESPIRATORY MEDICINE, 2023, 17 (09) : 743 - 751
  • [48] A RAS Renaissance: Emerging Targeted Therapies for KRAS-Mutated Non-Small Cell Lung Cancer
    Vasan, Neil
    Boyer, Julie L.
    Herbst, Roy S.
    CLINICAL CANCER RESEARCH, 2014, 20 (15) : 3921 - 3930
  • [49] Basroparib overcomes acquired resistance to MEK inhibitors by inhibiting Wnt-mediated cancer stemness in KRAS-mutated colorectal cancer
    Kwon, Young-Ju
    Kim, Dong Young
    Kim, Uk-Il
    Kim, Song Hyun
    Kim, Ye-hyun
    Kim, Kyungjin
    Kim, Jae-Sung
    BIOCHEMICAL PHARMACOLOGY, 2025, 235
  • [50] Phase I study of FOLFIRI plus pimasertib as second-line treatment for KRAS-mutated metastatic colorectal cancer
    Macarulla, T.
    Cervantes, A.
    Tabernero, J.
    Rosello, S.
    Van Cutsem, E.
    Tejpar, S.
    Prenen, H.
    Martinelli, E.
    Troiani, T.
    Laffranchi, B.
    Jego, V.
    von Richter, O.
    Ciardiello, F.
    BRITISH JOURNAL OF CANCER, 2015, 112 (12) : 1874 - 1881