A case of postoperative pancreatitis in patients with renal cell carcinoma with an inferior vena cava tumor thrombus treated by presurgical lenvatinib plus pembrolizumab

被引:1
作者
Kurokawa, Masahiro [1 ,2 ]
Ikarashi, Daiki [1 ]
Kato, Renpei [1 ]
Kanehira, Mitsugu [1 ]
Fukagai, Takashi [2 ]
Obara, Wataru [1 ]
机构
[1] Iwate Med Univ, Dept Urol, Sch Med, 2-1-1 Idaidori,Yahaba Cho, Morioka, Iwate 0283695, Japan
[2] Showa Univ, Sch Med, Dept Urol, Tokyo, Japan
关键词
Pembrolizumab; Lenvatinib; Renal cell carcinoma; Inferior vena cava thrombus; Pancreatitis;
D O I
10.1007/s13691-024-00657-7
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Pancreatic injury is a rare, but noted complication of nephrectomy. We report a case involving a 56-year-old man who presented with cT3bN0M0 left locally advanced renal cell carcinoma with an inferior vena cava thrombus. Nephrectomy with thrombectomy was performed given the remarkable shrinkage of the primary tumor and thrombus following lenvatinib plus pembrolizumab administration. The patient developed postoperative pancreatitis associated with unrecognized minor pancreatic injury, which was treated conservatively. To our knowledge, this has been the first case that underwent nephrectomy for RCC with an IVC thrombus after presurgical lenvatinib plus pembrolizumab and received conservative treatment for postoperative pancreatitis.
引用
收藏
页码:158 / 161
页数:4
相关论文
共 50 条
[41]   Surgical management of renal cell carcinoma with subhepatic inferior vena cava tumor thrombus: a case report and review of the literature [J].
Ademi, Bekim ;
Jaha, Luan ;
Haxhiu, Isa ;
Cuni, Xhevdet ;
Tahiri, Afrim ;
Gashi, Jetmir ;
Koshi, Adhurim ;
Jaha, Art .
JOURNAL OF MEDICAL CASE REPORTS, 2024, 18 (01)
[42]   Case report: Anesthetic management for removal of tumor thrombus in the inferior vena cava and pulmonary artery in renal cell carcinoma [J].
Chen, Suli ;
Lu, Liangyuan ;
Zheng, Xiangli ;
Lin, Yanjun ;
Bao, Liming ;
Zhang, Bao ;
Yang, Zhanmin .
FRONTIERS IN ONCOLOGY, 2024, 14
[43]   Epithelioid Angiomyolipoma with Tumor Thrombus into Inferior Vena Cava Presurgically Treated with Combination Therapy of Pembrolizumab and Axitinib: A Case Report [J].
Kawasoe, Chihiro ;
Miyamoto, Yoshi ;
Ito, Kaoru ;
Murashima, Takaya ;
Nagai, Takahiro ;
Takamori, Hiroki ;
Kiwaki, Takumi ;
Kamimura, Toshio ;
Mukai, Shoichiro ;
Kamoto, Toshiyuki .
RESEARCH AND REPORTS IN UROLOGY, 2023, 15 :447-452
[44]   Incidental Finding of Renal Cell Carcinoma: Detected by a Thrombus in the Inferior Vena Cava [J].
Bellman, Nancy L. .
JOURNAL OF DIAGNOSTIC MEDICAL SONOGRAPHY, 2015, 31 (02) :118-121
[45]   A different approach in the treatment of left renal cell carcinoma with tumor thrombus extension into the vena cava inferior [J].
Gedik, Hikmet Selcuk ;
Alp, Ibrahim ;
Arslan, Gokhan ;
Dereli, Yuksel ;
Korkmaz, Kemal ;
Yilmaz, Ahmet Turan .
TURK GOGUS KALP DAMAR CERRAHISI DERGISI-TURKISH JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 2012, 20 (02) :396-398
[46]   Inferior vena cava interruption in renal cell carcinoma with tumor thrombus: surgical strategy and perioperative results [J].
Liu, Zhuo ;
Zhang, Qiming ;
Zhao, Xun ;
Zhu, Guodong ;
Tang, Shiying ;
Hong, Peng ;
Ge, Liyuan ;
Zhang, Shudong ;
Wang, Guoliang ;
Tian, Xiaojun ;
Zhang, Hongxian ;
Liu, Cheng ;
Ma, Lulin .
BMC SURGERY, 2021, 21 (01)
[47]   Robotic surgical techniques and methods for treating renal cell carcinoma with inferior vena cava tumor thrombus [J].
Luo, Jin ;
Li, Zhuoran ;
Liu, Qiwei ;
Jia, Yuqi ;
Li, Jinqiao ;
Zhao, Houming ;
Chen, Zhiqiang ;
Dong, Yujie ;
Zhang, Xu ;
Ma, Xin ;
Huang, Qingbo ;
Peng, Cheng ;
Wang, Baojun .
CURRENT UROLOGY, 2025, 19 (03) :177-186
[48]   Lenvatinib plus pembrolizumab combination therapy for adult patients with advanced renal cell carcinoma [J].
Ged, Yasser ;
Lee, Chung-Han .
EXPERT REVIEW OF ANTICANCER THERAPY, 2022, 22 (10) :1049-1059
[49]   Inferior vena cava interruption in renal cell carcinoma with tumor thrombus: surgical strategy and perioperative results [J].
Zhuo Liu ;
Qiming Zhang ;
Xun Zhao ;
Guodong Zhu ;
Shiying Tang ;
Peng Hong ;
Liyuan Ge ;
Shudong Zhang ;
Guoliang Wang ;
Xiaojun Tian ;
Hongxian Zhang ;
Cheng Liu ;
Lulin Ma .
BMC Surgery, 21
[50]   Stereotactic Body Radiation Therapy (SBRT) for Renal Cell Carcinoma with Inferior Vena Cava Tumor Thrombus [J].
Solomon, Ilona Pilosov ;
Mizrahi, Gal Rinott ;
Klein, Ilan ;
Dekel, Yoram ;
Freifeld, Yuval .
CANCERS, 2025, 17 (04)