Association of oral health with risk of incident micro and macrovascular complications: A prospective cohort study of 24,862 people with diabetes

被引：6

作者：

Gibson, Alice A. ^{[1
,2
,9
]}

Cox, Emma ^{[1
,2
]}

Gale, Joanne ^{[1
]}

Craig, Maria E. ^{[2
,3
]}

King, Shalinie ^{[4
,5
]}

Chow, Clara K. ^{[2
,4
,6
]}

Colagiuri, Stephen ^{[2
,7
]}

Nassar, Natasha ^{[1
,2
,8
]}

机构：

[1] Univ Sydney, Fac Med & Hlth, Menzies Ctr Hlth Policy & Econ, Sydney Sch Publ Hlth, Camperdown, NSW, Australia

[2] Univ Sydney, Charles Perkins Ctr, Camperdown, NSW, Australia

[3] UNSW Med & Hlth, Sch Clin Med, Discipline Paediat & Child Hlth, Sydney, NSW, Australia

[4] Univ Sydney, Fac Med & Hlth, Westmead Appl Res Ctr, Camperdown, NSW, Australia

[5] Univ Sydney, Fac Med & Heath, Sydney Dent Sch, Camperdown, NSW, Australia

[6] Westmead Hosp, Dept Cardiol, Westmead, NSW, Australia

[7] Univ Sydney, Fac Med & Hlth, Camperdown, NSW, Australia

[8] Univ Sydney, Childrens Hosp Westmead Clin Sch, Fac Med & Hlth, Child Populat & Translat Hlth Res, Camperdown, NSW, Australia

[9] Univ Sydney, Charles Perkins Ctr, Level 2, Camperdown, NSW 2006, Australia

来源：

DIABETES RESEARCH AND CLINICAL PRACTICE | 2023年 / 203卷

关键词：

Cohort study; Diabetes mellitus; Epidemiology; Diabetes complications; Oral health; Tooth loss; Cardiovascular disease; PERIODONTITIS; DISEASE;

D O I：

10.1016/j.diabres.2023.110857

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Aims: To investigate the association between self-reported oral health and incident micro and macrovascular diabetes complications. Methods: This prospective cohort study linked data from the 45 and Up Study, Australia, to administrative health records. The participants were 24,862 men and women, aged >= 45 years, with diabetes at baseline (2006-2009). The oral health of participants was assessed by questionnaire. Incident diabetes complications were determined using hospitalisation data and claims for medical services up until 2019. Hazard ratios for the association between oral health and incident complications were calculated using multivariable cox proportional hazards models.Results: Almost 60 % of participants had <20 teeth, and 38 % rated their teeth and gums as fair or poor. Compared with those with >= 20 teeth, those with 0 teeth had an increased risk of cardiovascular disease (aHR 1.24, 95 % CI: 1.15, 1.35), lower limb (aHR 1.22, 95 % CI: 1.11, 1.33) and kidney (aHR 1.19, 95 % CI: 1.11, 1.29) complications. Individuals with 1-9 teeth had an increased risk of eye complications (aHR 1.14, 95 % CI: 1.07, 1.22). The associations were generally consistent for poor self-rated teeth and gums. Conclusions: Self-reported oral health measures may be a marker of elevated risk of complications in people with diabetes.

引用

页数：10

共 42 条

[21] Oral disease and subsequent cardiovascular disease in people with type 2 diabetes: a prospective cohort study based on the Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified-Release Controlled Evaluation (ADVANCE) trial [J].