A framework for concepts of reserve and resilience in aging

被引：162

作者：

Stern, Yaakov ^{[1
,8
]}

Albert, Marilyn ^{[2
]}

Barnes, Carol A. ^{[3
,4
]}

Cabeza, Roberto ^{[5
]}

Pascual-Leone, Alvaro ^{[6
]}

Rapp, Peter R. ^{[7
]}

机构：

[1] Columbia Univ Vagelos Coll Phys & Surg, Dept Neurol, Cognit Neurosci Div, New York, NY USA

[2] Johns Hopkins Univ, Dept Psychiat & Neurol, Baltimore, MD USA

[3] Univ Arizona, Dept Psychol Neurol & Neurosci, Tucson, AZ USA

[4] Univ Arizona, Evelyn F McKnight Brain Inst, Tucson, AZ USA

[5] Duke Univ, Ctr Cognit Neurosci, Dept Psychol & Neurosci, Durham, NC USA

[6] Harvard Med Sch, Dept Neurol, Boston, MA USA

[7] Natl Inst Aging, Neurocognit Aging Sect, Lab Behav Neurosci, Baltimore, MD USA

[8] Columbia Univ, Vagelos Coll Phys & Surg, 630 168th St,P&S Box 16, New York, NY 10032 USA

来源：

NEUROBIOLOGY OF AGING | 2023年 / 124卷

基金：

美国国家卫生研究院;

关键词：

Resilience; Cognitive reserve; Brain maintenance; Brain reserve;

D O I：

10.1016/j.neurobiolaging.2022.10.015

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

The study of factors, across species, that allow some individuals to age more successfully than others has important implications for individual wellbeing as well as health education, policy and intervention. De-sign of studies and communication across investigators in this area has been hampered by a diversity of terminology. The Collaboratory on Research Definitions for Reserve and Resilience in Cognitive Aging and Dementia was funded by the National Institute on Aging and established in 2019 as a 3-year process of developing consensus definitions and research guidelines. The proposed Framework is based on an itera-tive process including 3 annual Workshops, focused workgroups, and input from numerous international investigators. It suggests the overarching term: resilience, and presents operational definitions for 3 con-cepts: cognitive reserve, brain maintenance, and brain reserve. Twelve pilot studies that integrate these definitions are presented. The use of a common vocabulary and operational definitions will facilitate even greater progress in understanding the factors that are associated with successful aging. (c) 2022 Elsevier Inc. All rights reserved.

引用

页码：100 / 103

页数：4