Sarcoidosis Associated with Enlarged Mediastinal Lymph Nodes with the Detection of Streptococcus gordonii and Cutibacterium acnes Using a Clone Library Method

被引：1

作者：

Akata, Kentaro ^{[1
]}

Yamasaki, Kei ^{[2
]}

Nemoto, Kazuki ^{[2
]}

Ikegami, Hiroaki ^{[2
,4
]}

Kawaguchi, Takako ^{[2
]}

Noguchi, Shingo ^{[2
]}

Kawanami, Toshinori ^{[2
]}

Fukuda, Kazumasa ^{[3
]}

Mukae, Hiroshi

Yatera, Kazuhiro ^{[2
]}

机构：

[1] Univ Occupat & Environm Hlth, Div Infect Control & Prevent, Kitakyushu, Japan

[2] Univ Occupat & Environm Hlth, Dept Resp Med, Kitakyushu, Japan

[3] Univ Occupat & Environm Hlth, Dept Microbiol, Kitakyushu, Japan

[4] Nagasaki Univ, Grad Sch Biomed Sci, Dept Resp Med, Nagasaki, Japan

来源：

INTERNAL MEDICINE | 2024年 / 63卷 / 02期

关键词：

sarcoidosis; bacterial flora; 16S ribosomal RNA gene analysis; MYCOBACTERIAL CATALASE-PEROXIDASE; POLYMERASE-CHAIN-REACTION; PROPIONIBACTERIUM-ACNES; PULMONARY-FIBROSIS; RIBOSOMAL-RNA; CT FINDINGS; DNA; ANAEROBES; ANTIGEN;

D O I：

10.2169/internalmedicine.1887-23

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A 77-year-old Japanese woman with mediastinal lymphadenopathy and uveitis was diagnosed with sarcoi-dosis. The bacterial flora in biopsied samples from mediastinal lymph nodes was analyzed using a clone li-brary method with Sanger sequencing of the 16S rRNA gene, and Streptococcus gordonii (52 of 71 clones) and Cutibacterium acnes (19 of 71 clones) were detected. No previous study has conducted a bacterial floral analysis using the Sanger method for the mediastinal lymph node in sarcoidosis, making this case report the first to document the presence of S. gordonii and C. acnes in the mediastinal lymph node of a patient with sarcoidosis.

引用

页码：299 / 304

页数：6

共 43 条

[41] Significance of Anaerobes and Oral Bacteria in Community-Acquired Pneumonia
Yamasaki, Kei
Kawanami, Toshinori
Yatera, Kazuhiro
Fukuda, Kazumasa
Noguchi, Shingo
Nagata, Shuya
Nishida, Chinatsu
Kido, Takashi
Ishimoto, Hiroshi
Taniguchi, Hatsumi
Mukae, Hiroshi
[J]. PLOS ONE, 2013, 8 (05):
[42] The microbiome in the lower respiratory tract
Yatera, Kazuhiro
Noguchi, Shingo
Mukae, Hiroshi
[J]. RESPIRATORY INVESTIGATION, 2018, 56 (06) : 432 - 439
[43] Real-time quantitative reverse transcription-polymerase chain reaction to detect propionibacterial ribosomal RNA in the lymph nodes of Chinese patients with sarcoidosis
Zhou, Y.
Wei, Y. -R.
Zhang, Y.
Du, S. -S.
Baughman, R. P.
Li, H. -P.
[J]. CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 2015, 181 (03) : 511 - 517

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