Progress of fluorescent probes for protein phosphorylation and glycosylation in atherosclerosis

被引：0

作者：

Li, Jin ^{[1
]}

Xu, Jiheng ^{[2
]}

Zhao, Ruize ^{[1
]}

Zhang, Wei ^{[1
]}

Li, Ping ^{[1
]}

Zhang, Wen ^{[1
]}

Wang, Hui ^{[1
]}

Tang, Bo ^{[1
,3
]}

机构：

[1] Shandong Normal Univ, Collaborat Innovat Ctr Functionalized Probes Chem, Coll Chem Chem Engn & Mat Sci,Inst Biomed Sci, Key Lab Mol & Nano Probes,Minist Educ, Jinan 250014, Peoples R China

[2] Shandong Univ, Sch Mat Sci & Engn, Jinan 250014, Peoples R China

[3] Laoshan Lab, Qingdao 266237, Peoples R China

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2024年 / 30卷 / 18期

基金：

中国国家自然科学基金; 国家重点研发计划;

关键词：

atherosclerosis; phosphorylation; glycosylation; fluorescent probe; biomarker; CROSS-TALK; CELL; VISUALIZATION; RECOGNITION; RECEPTORS; DISEASES; PEPTIDE;

D O I：

10.1002/chem.202303778

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Exploring the post-translational modification (PTM) of proteins in the course of atherosclerotic disease has important guiding significance for the early warning of atherosclerotic plaque, the development of targeted drugs and the treatment of disease. The advancement advanced detection and imaging methods for phosphorylated and glycosylated proteins is an important tool to further reveal the levels of protein phosphorylation and glycosylation during atherosclerotic plaque formation. We present research strategies for detecting protein phosphorylation and glycosylation from the perspective of fluorescent probes, and discuss the feasibility and future direction of the development of these methods for detecting and imaging phosphorylated and glycosylated proteins in atherosclerotic disease. Exploring the post-translational modification (PTM) of proteins in the course of atherosclerotic disease has important guiding significance for the early warning of atherosclerotic plaque and the development of targeted drugs. We present strategies for detecting protein phosphorylation and glycosylation from the perspective of fluorescent probes, and discuss the problems and future directions of these methods+image

引用

页数：9

共 50 条

[21] Progresses and applications of protein fluorescent probes [J].

Chen Zhenzhen ;

Zhang Ning ;

Zhang Wenshen ;

Tang Bo .

CHINESE JOURNAL OF ANALYTICAL CHEMISTRY, 2006, 34 (09) :1341-1347

[22] Recent Progress of Natural and Recombinant Phycobiliproteins as Fluorescent Probes [J].

Chen, Huaxin ;

Deng, Jinglong ;

Li, Longqi ;

Liu, Zhe ;

Sun, Shengjie ;

Xiong, Peng .

MARINE DRUGS, 2023, 21 (11)

[23] Design, Synthesis, Application and Research Progress of Fluorescent Probes [J].

Xingxiu Jiang ;

Ruizhu Yang ;

Xueli Lei ;

Shun Xue ;

Zhe Wang ;

Jinyang Zhang ;

Lan Yan ;

Zhiyi Xu ;

Zhengcheng Chen ;

Ping Zou ;

Guangtu Wang .

Journal of Fluorescence, 2024, 34 :965-975

[24] Progress of Fluorescent Probes with Perylene Tetracarboxylic Diimide as Chromophore [J].

Shi, Yan ;

Yu, Youwei ;

Xue, Lin ;

Wang, Yanfeng .

CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2019, 39 (12) :3414-3437

[25] Recent Progress in Fluorescent Probes for the Detection of Hypochlorous Acid [J].

Wang, Yanbao ;

Zhao, Baoxiang .

CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2016, 36 (07) :1539-1554

[26] Design, Synthesis, Application and Research Progress of Fluorescent Probes [J].

Jiang, Xingxiu ;

Yang, Ruizhu ;

Lei, Xueli ;

Xue, Shun ;

Wang, Zhe ;

Zhang, Jinyang ;

Yan, Lan ;

Xu, Zhiyi ;

Chen, Zhengcheng ;

Zou, Ping ;

Wang, Guangtu .

JOURNAL OF FLUORESCENCE, 2024, 34 (03) :965-975

[27] Recent Progress in Ratiometric Fluorescent Probes Based on Excitation Energy Transfer Mechanism [J].

Chen, Zhonglin ;

Li, Hongling ;

Wei, Jia ;

Xiao, Yi ;

Yu, Haibo .

CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2015, 35 (04) :789-801

[28] Recent Progress on Endoplasmic Reticulum-Targetable Small Organic Fluorescent Probes [J].

Zhang, Shengxi ;

Niu, Qingmin ;

Wu, Songze ;

Lu, Haijuan ;

Xing, Guowen .

CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2019, 39 (04) :940-951

[29] Effects of Phosphorylation and Glycosylation on the Digestibility of Soybean Protein in Vitro [J].

Liu J. ;

Wang R. ;

Lü Y. ;

Guo S. ;

Xing J. ;

Yang B. .

Journal of Chinese Institute of Food Science and Technology, 2021, 21 (02) :89-99

[30] Isolation of a glycosylated form of the chicken eggshell protein ovocleidin and determination of the glycosylation site.: Alternative glycosylation/phosphorylation at an N-glycosylation sequon [J].

Mann, K .

FEBS LETTERS, 1999, 463 (1-2) :12-14

← 1 2 3 4 5 →