Relationship between Lower Extremity Peripheral Arterial Disease and Mild Cognitive Impairment in Hemodialysis Patients

被引:2
作者
Nishimura, Akinori [1 ]
Hidaka, Sumi [2 ,3 ]
Kawaguchi, Takayuki [4 ]
Watanabe, Aki [5 ]
Mochida, Yasuhiro [2 ]
Ishioka, Kunihiro [2 ]
Mwanatanbwe, Milanga [6 ,7 ]
Ohtake, Takayasu [2 ,3 ]
Kobayashi, Shuzo [2 ,3 ]
机构
[1] Shonan Kamakura Gen Hosp, Rehabil Unit, Okamoto 1370-1, Kamakura 2478533, Japan
[2] Shonan Kamakura Gen Hosp, Kidney Dis & Transplant Ctr, Kamakura 2478533, Japan
[3] Shonan Res Inst Innovat Med sRIIM, Kamakura 2478533, Japan
[4] Natl Ctr Neurol & Psychiat, Natl Inst Mental Hlth, Dept Community Mental Hlth & Law, Kodaira 1878553, Japan
[5] Kitasato Univ, Sch Allied Hlth Sci, Sagamihara 2520373, Japan
[6] Univ Mbuji Mayi, Dept Pathol, Mbuji Mayi 8010, DEM REP CONGO
[7] Int Div Tokushukai Med Corp, Chiyoda Ku, Tokushukai 1020074, Japan
关键词
hemodialysis; mild cognitive impairment; peripheral artery disease; lower extremity artery disease; ankle brachial index; toe brachial index; CHRONIC KIDNEY-DISEASE; ANKLE-BRACHIAL INDEX; BRIEF SCREENING TOOL; RENAL-INSUFFICIENCY; RISK-FACTORS; DIALYSIS; MORTALITY; DEMENTIA; BRAIN; HEART;
D O I
10.3390/jcm12062145
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background: The link between arterial stiffness and mild cognitive impairment (MCI) in patients on hemodialysis (HD) has been receiving increased attention. The purpose of this study was to investigate the relationship between cognitive function and ankle brachial index (ABI) and toe brachial index (TBI) values in patients on hemodialysis. Of the 100 participants (mean age: 67.9 years; average history of hemodialysis: 7.3 years). Of these, 46.0% had MCI. The MoCA-J scores were significantly higher in the ABI >= 1.06 group. However, the MoCA-J scores divided into the two groups according to the TBI cutoff value were not significantly different. In a multiple regression model with the MoCA-J scores as the objective variable, the ABI was a significantly associated factor. This study indicates that a low ABI might be associated with MCI.
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页数:11
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