Occult metastases of oral maxillary squamous cell carcinoma: Systematic review and meta-analysis

被引：7
|
作者：
de la Fuente, Carlos [1 ,2 ]
Prat-Valero, Nil [1 ,2 ]
Alberola-Ferranti, Margarita [3 ]
Mis-Castell, David [1 ,2 ]
Saez-Barba, Manel [1 ,2 ]
Pujol-Pina, Rosa [2 ]
Pamias-Romero, Jorge [1 ,2 ]
Bescos-Atin, Coro [1 ,2 ]
机构：
[1] Vall dHebron Hosp Univ, Serv Cirurgia Oral & Maxillofacial, Vall dHebron Barcelona Hosp Campus, Barcelona 08035, Spain
[2] Vall dHebron Hosp Univ, Vall dHebron Inst Recerca VHIR, CIBBIM Nanomed Noves Tecnol & Microcirurgia Crani, Vall dHebron Barcelona Hosp Campus, Barcelona, Spain
[3] Vall dHebron Hosp Univ, Serv Anat Patol, Vall dHebron Barcelona Hosp Campus, Barcelona, Spain
来源：
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK | 2023年 / 45卷 / 03期
关键词：
cervical metastases; elective neck dissection; maxillary gingiva; occult metastases; squamous cell carcinoma; ELECTIVE NECK DISSECTION; CERVICAL METASTASES; HARD PALATE; RETROSPECTIVE ANALYSIS; NEGATIVE NECK; ALVEOLUS; MANAGEMENT; SURVIVAL; IMPACT; PREDICTORS;
D O I：
10.1002/hed.27276
中图分类号：
R76 [耳鼻咽喉科学];
学科分类号：
100213 ;
摘要：
Squamous cell carcinoma (SCC) is the most common malignant neoplasm of the oral cavity. The performance of END (elective neck dissection) in cases of maxillary SCC is controversial because the literature traditionally classified maxillary tumors as having low metastatic potential. The aim of this systematic review and meta-analysis was to determine the percentage of occult cervical metastases in maxillary SCC to identify in which cases there is the need to perform an END. We searched the PubMed database to select articles dated from 2000 to 2020 that fulfilled our inclusion criteria; finally, we reviewed 27 manuscripts. We show that the overall cervical and occult metastases rate was 35% and 19%, respectively. For T1, the percentage of occult metastasis rate was 11%; for T2, it was 16%; for T3, it was 20%; and for T4, it was 32%. We suggest END (levels I-II-III) as treatment to T3/T4 cN0 patients.
引用
收藏
页码：733 / 744
页数：12
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