Distinctive magnetic resonance imaging features in primary central nervous system lymphoma: A case report

被引：0
作者：
Liu, Li-Hong [1 ]
Zhang, Han-Wen [1 ,2 ,5 ]
Zhang, Hong-Bo [2 ,3 ]
Liu, Xiao-Lei [1 ]
Deng, Hua-Zhen [1 ]
Lin, Fan [1 ]
Huang, Biao [2 ,4 ]
机构：
[1] Shenzhen Univ, Shenzhen Peoples Hosp 2, Hlth Sci Ctr, Dept Radiol,Affiliated Hosp 1, Shenzhen 518036, Guangdong, Peoples R China
[2] Southern Med Univ, Sch Clin Med 2, Guangzhou 510282, Guangdong, Peoples R China
[3] Sun Yat Sen Univ, Dept Radiol, Shenzhen 518000, Guangdong, Peoples R China
[4] Guangdong Acad Med Sci, Guangdong Prov Peoples Hosp, Dept Radiol, Guangzhou 510000, Guangdong, Peoples R China
[5] Shenzhen Univ, Shenzhen Peoples Hosp 2, Hlth Sci Ctr, Dept Radiol,Affiliated Hosp 1, 3002 Sungangxi Rd, Shenzhen 518036, Guangdong, Peoples R China
来源：
WORLD JOURNAL OF RADIOLOGY | 2023年 / 15卷 / 09期
基金：
中国国家自然科学基金;
关键词：
Primary central nervous system lymphoma; Diffusion-weighted imaging; Perfusion-weighted imaging; Magnetic resonance imaging; Case report; DIFFERENTIATION; MRI;
D O I：
10.4329/wjr.v15.i9.274
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
BACKGROUND Primary central nervous system lymphoma (PCNSL) is a rare malignant tumor originating from the lymphatic hematopoietic system. It exhibits unique imaging manifestations due to its biological characteristics. CASE SUMMARY Magnetic resonance imaging (MRI) with diffusion-weighted imaging (DWI), perfusion-weighted imaging (PWI), and magnetic resonance spectroscopy was performed. The imaging findings showed multiple space-occupying lesions with low signal on T1-weighted imaging, uniform high signal on T2-weighted imaging, and obvious enhancement on contrast-enhanced scans. DWI revealed diffusion restriction, PWI demonstrated hypoperfusion, and spectroscopy showed elevated choline peak and decreased N-acetylaspartic acid. The patient's condition significantly improved after hormone shock therapy. CONCLUSION This case highlights the distinctive imaging features of PCNSL and their importance in accurate diagnosis and management.
引用
收藏
页数：8
相关论文
共 13 条
  • [1] Consensus recommendations for MRI and PET imaging of primary central nervous system lymphoma: guideline statement from the International Primary CNS Lymphoma Collaborative Group (IPCG)
    Barajas, Ramon F., Jr.
    Politi, Letterio S.
    Anzalone, Nicoletta
    Schoder, Heiko
    Fox, Christopher P.
    Boxerman, Jerrold L.
    Kaufmann, Timothy J.
    Quarles, C. Chad
    Ellingson, Benjamin M.
    Auer, Dorothee
    Andronesi, Ovidiu C.
    Ferreri, Andres J. M.
    Mrugala, Maciej M.
    Grommes, Christian
    Neuwelt, Edward A.
    Ambady, Prakash
    Rubenstein, James L.
    Illerhaus, Gerald
    Nagane, Motoo
    Batchelor, Tracy T.
    Hu, Leland S.
    [J]. NEURO-ONCOLOGY, 2021, 23 (07) : 1056 - 1071
  • [2] Role of intra-tumoral vasculature imaging features on susceptibility weighted imaging in differentiating primary central nervous system lymphoma from glioblastoma: a multiparametric comparison with pathological validation
    Bhattacharjee, Rupsa
    Gupta, Mamta
    Singh, Tanu
    Sharma, Shalini
    Khanna, Gaurav
    Parvaze, Suhail P.
    Patir, Rana
    Vaishya, Sandeep
    Ahlawat, Sunita
    Singh, Anup
    Gupta, Rakesh Kumar
    [J]. NEURORADIOLOGY, 2022, 64 (09) : 1801 - 1818
  • [3] The clinical analysis of new-onset status epilepticus
    Deng, Binlu
    Dai, Yuqian
    Wang, Qi
    Yang, Jie
    Chen, Xiang
    Liu, Ting-Ting
    Liu, Jie
    [J]. EPILEPSIA OPEN, 2022, 7 (04) : 771 - 780
  • [4] Diagnostic Accuracy of the Diffusion-Weighted Imaging Method Used in Association With the Apparent Diffusion Coefficient for Differentiating Between Primary Central Nervous System Lymphoma and High-Grade Glioma: Systematic Review and Meta-Analysis
    Du, Xiaoli
    He, Yue
    Lin, Wei
    [J]. FRONTIERS IN NEUROLOGY, 2022, 13
  • [5] Differentiation Between Primary Central Nervous System Lymphoma and Atypical Glioblastoma Based on MRI Morphological Feature and Signal Intensity Ratio: A Retrospective Multicenter Study
    Han, Yu
    Wang, Zi-Jun
    Li, Wen-Hua
    Yang, Yang
    Zhang, Jian
    Yang, Xi-Biao
    Zuo, Lin
    Xiao, Gang
    Wang, Sheng-Zhong
    Yan, Lin-Feng
    Cui, Guang-Bin
    [J]. FRONTIERS IN ONCOLOGY, 2022, 12
  • [6] Differentiation between glioblastoma and primary CNS lymphoma: application of DCE-MRI parameters based on arterial input function obtained from DSC-MRI
    Kang, Koung Mi
    Choi, Seung Hong
    Chul-Kee, Park
    Kim, Tae Min
    Park, Sung-Hye
    Lee, Joo Ho
    Lee, Soon-Tae
    Hwang, Inpyeong
    Yoo, Roh-Eul
    Yun, Tae Jin
    Kim, Ji-Hoon
    Sohn, Chul-Ho
    [J]. EUROPEAN RADIOLOGY, 2021, 31 (12) : 9098 - 9109
  • [7] Krebs Simone, 2021, Ann Lymphoma, V5, DOI 10.21037/aol-20-52
  • [8] Diagnostic Accuracy of T1-Weighted Dynamic Contrast-Enhanced-MRI and DWI-ADC for Differentiation of Glioblastoma and Primary CNS Lymphoma
    Lin, X.
    Lee, M.
    Buck, O.
    Woo, K. M.
    Zhang, Z.
    Hatzoglou, V.
    Omuro, A.
    Arevalo-Perez, J.
    Thomas, A. A.
    Huse, J.
    Peck, K.
    Holodny, A. I.
    Young, R. J.
    [J]. AMERICAN JOURNAL OF NEURORADIOLOGY, 2017, 38 (03) : 485 - 491
  • [9] Neurolymphomatosis in Intravascular Large B-cell Lymphoma
    Miyajima, Toru
    Ohigashi, Hiroyuki
    Yaguchi, Hiroaki
    Teshima, Takanori
    [J]. INTERNAL MEDICINE, 2023, 62 (09) : 1381 - 1382
  • [10] Primary central nervous system lymphoma
    Schaff, Lauren R.
    Grommes, Christian
    [J]. BLOOD, 2022, 140 (09) : 971 - 979
12