Recent Advances in the Synthesis and Applications of Phenylquinoline-4-carboxylic Acid Derivatives: A Comprehensive Review

被引：1
作者：
Saha, Sunam [1 ]
Pathak, Devender [2 ]
Shah, Kamal [1 ]
机构：
[1] GLA Univ, Inst Pharmaceut Res, Dept Pharmaceut Chem, Mathura, Uttar Pradesh, India
[2] Rajiv Acad Pharm, Dept Pharmaceut Chem, Mathura, Uttar Pradesh, India
来源：
CURRENT ORGANIC CHEMISTRY | 2024年 / 28卷 / 01期
关键词：
Phenylquinoline-4-carboxylic acid derivatives; material science; antibacterial; antifungal; anti-malarial; antiviral activities; medicinal chemistry; MICROWAVE-ASSISTED SYNTHESIS; QUINOLINE DERIVATIVES; DESIGN; CHEMISTRY;
D O I：
10.2174/0113852728279082231226061243
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Phenylquinoline-4-carboxylic acid derivatives have garnered significant attention in recent years due to their diverse pharmacological and industrial applications. This comprehensive review summarizes the latest advancements in the synthesis and diverse range of applications of phenylquinoline-4-carboxylic acid derivatives. This review provides a brief overview of the significance of phenylquinoline-4-carboxylic acid derivatives in medicinal chemistry. It also explores the structural diversity achievable through modifications at various positions of the phenylquinoline-4-carboxylic acid scaffold. The pharmacological applications of phenylquinoline-4-carboxylic acid derivatives, such as anticancer, antimicrobial, anti-inflammatory, and antiviral activities, are highlighted, underscoring their potential as promising drug candidates. This comprehensive review provides a thorough overview of the recent advances in the synthesis and applications of phenylquinoline-4-carboxylic acid derivatives. The integration of synthetic methodologies, structural modifications and diverse applications makes this review a valuable resource for researchers, scientists and professionals working in the fields of medicinal chemistry.
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页码：9 / 20
页数：12
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