Alcohol consumption and opioid craving among chronic pain patients prescribed long-term opioid therapy

被引:2
作者
Odette, Madeleine M. [1 ,2 ,3 ]
Porucznik, Christina A. [1 ]
Gren, Lisa H. [1 ]
Garland, Eric L. [2 ,3 ,4 ]
机构
[1] Univ Utah, Dept Family & Preventat Med, Div Publ Hlth, Spencer Fox Eccles Sch Med, Salt Lake City, UT USA
[2] Univ Utah, Ctr Mindfulness & Integrat Hlth Intervent Dev, Salt Lake City, UT 84112 USA
[3] Univ Utah, Coll Social Work, 395 South 1500 East, Salt Lake City, UT 84112 USA
[4] Univ Utah, 395 South,1500 East, Salt Lake City, UT 84112 USA
关键词
Opioids; Craving; Alcohol; Chronic pain; Opioid misuse; DRUG-USE; MISUSE; VULNERABILITY; IMPULSIVITY; ADDICTION; CONTEXT; NEUROBIOLOGY; PREVALENCE; VALIDATION; BEHAVIOR;
D O I
10.1016/j.addbeh.2023.107911
中图分类号
B849 [应用心理学];
学科分类号
040203 ;
摘要
Background: Concurrent use of alcohol with opioids is common among chronic pain patients, heightening the risk for disordered opioid use and overdose, yet the relationship between alcohol consumption and opioid craving among chronic pain patients remains largely unexplored. Here we examined the relationship between alcohol consumption and opioid craving among chronic pain patients on long-term opioid therapy.Methods: A cross-sectional study was conducted with 335 chronic pain patients on long-term opioid therapy. Participants completed the Timeline Followback to assess alcohol consumption, as well as measures of opioid craving, pain severity, and pain interference. Linear regression analyses examined the relationship between alcohol consumption and opioid craving, controlling for pain severity, pain interference, and opioid misuse severity.Results: Alcohol consumption (total number of drinks and amount consumed in one sitting) was positively associated with opioid craving (p < 0.001 and p = 0.005, respectively). Pain severity did not predict opioid craving. The relationship between alcohol consumption and opioid craving remained significant after controlling for pain severity, pain interference, and opioid misuse severity.Conclusion: Alcohol consumption is linked with more severe opioid craving among chronic pain patients pre-scribed long-term opioid therapy. Patients receiving opioid analgesics should be carefully screened for co-use of alcohol.
引用
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页数:8
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