Plant-derived nanovesicles: Current understanding and applications for cancer therapy

被引：83

作者：

Ly, Ngoc Phung ^{[1
,2
]}

Han, Hwa Seung ^{[1
]}

Kim, Myungsuk ^{[1
]}

Park, Jae Hyung ^{[3
,4
,5
]}

Choi, Ki Young ^{[1
,2
]}

机构：

[1] Korea Inst Sci & Technol KIST, Nat Prod Informat Res Ctr, Kangnung 25451, South Korea

[2] Univ Sci & Technol UST, KIST Sch, Div Biomed Sci & Technol, Seoul 02792, South Korea

[3] Sungkyunkwan Univ, Coll Engn, Sch Chem Engn, Suwon 16419, South Korea

[4] Sungkyunkwan Univ, SAIHST, Dept Hlth Sci & Technol, Seoul 06351, South Korea

[5] Sungkyunkwan Univ, Biomed Inst Convergence SKKU, Suwon 16419, South Korea

来源：

BIOACTIVE MATERIALS | 2023年 / 22卷

关键词：

Plant-derived vesicles; Extracellular vesicles; Cancer therapy; Anti-cancer; Drug delivery; EXOSOME-LIKE NANOVESICLES; EXTRACELLULAR VESICLES; DRUG-DELIVERY; NANOPARTICLES; CELLS; INHIBIT; PROLIFERATION; DOXORUBICIN; SECRETION; INFECTION;

D O I：

10.1016/j.bioactmat.2022.10.005

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Plant-derived vesicles (PDVs) are membranous structures that originate from plant cells and are responsible for multiple physiological and pathological functions. In the last decade, PDVs have gained much attention for their involvement in different biological processes, including intercellular communication and defense response, and recent scientific evidence has opened a new avenue for their applications in cancer treatment. Nevertheless, much remains unknown about these vesicles, and current research remains inconsistent. This review aims to provide a comprehensive introduction to PDVs, from their biological characteristics to purification methods, and to summarize the status of their potential development for cancer therapy.

引用

页码：365 / 383

页数：19

共 103 条

[1] Do Plant Cells Secrete Exosomes Derived from Multivesicular Bodies? [J].

An, Qianli ;

van Bel, Aart J. E. ;

Hueckelhoven, Ralph .

PLANT SIGNALING & BEHAVIOR, 2007, 2 (01) :4-7

[2] Multivesicular compartments proliferate in susceptible and resistant MLA12-barley leaves in response to infection by the biotrophic powdery mildew fungus [J].

An, Qianli ;

Ehlers, Katrin ;

Kogel, Karl-Heinz ;

van Bel, Aart J. E. ;

Hueckelhoven, Ralph .

NEW PHYTOLOGIST, 2006, 172 (03) :563-576

[3] Uptake Pathway of Apple-derived Nanoparticle by Intestinal Cells to Deliver its Cargo [J].

Arai, Mayumi ;

Komori, Hisakazu ;

Fujita, Daichi ;

Tamai, Ikumi .

PHARMACEUTICAL RESEARCH, 2021, 38 (03) :523-530

[4] Plant Extracellular Vesicles Contain Diverse Small RNA Species and Are Enriched in 10-to 17-Nucleotide "Tiny" RNAs [J].

Baldrich, Patricia ;

Rutter, Brian D. ;

Karimi, Hana Zand ;

Podicheti, Ram ;

Meyers, Blake C. ;

Innes, Roger W. .

PLANT CELL, 2019, 31 (02) :315-324

[5] Use of Nanovesicles from Orange Juice to Reverse Diet-Induced Gut Modifications in Diet-Induced Obese Mice [J].

Berger, Emmanuelle ;

Colosetti, Pascal ;

Jalabert, Audrey ;

Meugnier, Emmanuelle ;

Wiklander, Oscar P. B. ;

Jouhet, Juliette ;

Errazurig-Cerda, Elisabeth ;

Chanon, Stephanie ;

Gupta, Dhanu ;

Rautureau, Gilles J. P. ;

Geloen, Alain ;

El-Andaloussi, Samir ;

Panthu, Baptiste ;

Rieusset, Jennifer ;

Rome, Sophie .

MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT, 2020, 18 :880-892

[6] Biomanufacturing of Tomato-Derived Nanovesicles [J].

Bokka, Ramesh ;

Ramos, Anna Paulina ;

Fiume, Immacolata ;

Manno, Mauro ;

Raccosta, Samuele ;

Turiak, Lilla ;

Sugar, Simon ;

Adamo, Giorgia ;

Csizmadia, Tamas ;

Pocsfalvi, Gabriella .

FOODS, 2020, 9 (12)

[7] Targeting phospholipase D in cancer, infection and neurodegenerative disorders [J].

Brown, H. Alex ;

Thomas, Paul G. ;

Lindsley, Craig W. .

NATURE REVIEWS DRUG DISCOVERY, 2017, 16 (05) :351-367

[8] Plants send small RNAs in extracellular vesicles to fungal pathogen to silence virulence genes [J].

Cai, Qiang ;

Qiao, Lulu ;

Wang, Ming ;

He, Baoye ;

Lin, Feng-Mao ;

Palmquist, Jared ;

Huang, Sienna-Da ;

Jin, Hailing .

SCIENCE, 2018, 360 (6393) :1126-1129

[9] Ginseng-derived nanoparticles alter macrophage polarization to inhibit melanoma growth [J].

Cao, Meng ;

Yan, Huaijiang ;

Han, Xuan ;

Weng, Ling ;

Wei, Qin ;

Sun, Xiaoyan ;

Lu, Wuguang ;

Wei, Qingyun ;

Ye, Juan ;

Cai, Xueting ;

Hu, Chunping ;

Yin, Xiaoyang ;

Cao, Peng .

JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2019, 7 (01)

[10] Natural exosome-like nanovesicles from edible tea flowers suppress metastatic breast cancer via ROS generation and microbiota modulation [J].

Chen, Qiubing ;

Li, Qian ;

Liang, Yuqi ;

Zu, Menghang ;

Chen, Nanxi ;

Canup, Brandon S. B. ;

Luo, Liyong ;

Wang, Chenhui ;

Zeng, Liang ;

Xiao, Bo .

ACTA PHARMACEUTICA SINICA B, 2022, 12 (02) :907-923

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