Two new cadinene-type sesquiterpene glycosides from Dendrobium findlayanum

被引：2
|
作者：
Cheng, Zhongquan [1 ]
Fan, Weiwei [2 ]
Yang, Dan [3 ,4 ]
Hu, Jiangmiao [5 ]
机构：
[1] Guangzhou Hlth Sci Coll, Coll Pharm, Guangzhou, Peoples R China
[2] Pingdingshan Univ, Coll Med, Henan Engn Res Ctr Funiu Mt Med Resources Utiliza, Pingdingshan, Peoples R China
[3] Guangdong Med Univ, Guangdong Prov Key Lab Res & Dev Nat Drugs, Dongguan, Peoples R China
[4] Guangdong Med Univ, Sch Pharm, Dongguan, Peoples R China
[5] Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming, Yunnan, Peoples R China
来源：
NATURAL PRODUCT RESEARCH | 2023年 / 37卷 / 21期
关键词：
Dendrobium findlayanum; Orchidaceae; cadinene-type esquiterpene glycoside; findlayanoside; DERIVATIVES; ALKALOIDS;
D O I：
10.1080/14786419.2022.2097228
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Two new and one known cadinene-type sesquiterpene glycosides, findlayanosides A-B (1-2) and dendronobiloside D (3), were isolated from the stems of Dendrobium findlayanum. This is the first report that cadinene-type sesquiterpene glycosides were isolated from D. findlayanum. The structures of compounds 1 and 2 were elucidated by extensive spectroscopic analyses, and their absolute configurations were confirmed by electronic circular dichroism (ECD) calculations. The obtained compounds were evaluated for their cytotoxicity against HL-60, SMMC-7721, A-549 and MCF-7 human cancer cells, and no obvious cytotoxic activity was observed at the concentration of 25 mu M. [GRAPHICS] .
引用
收藏
页码：3616 / 3622
页数：7
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