Selective photothermolysis with a novel 1726 nm laser beam: A safe and effective solution for acne vulgaris

被引:17
|
作者
Goldberg, David [1 ]
Kothare, Amogh [2 ]
Doucette, Margot [2 ]
Kaur, Arshdeep [2 ]
Ronan, Stephen [3 ]
Fromowitz, Jeffrey [4 ]
Hamidi-Sakr, Amer [2 ]
机构
[1] Icahn Sch Med Mt Sinai, Dermatol, New York, NY 10029 USA
[2] Cutera Inc, 3240 Bayshore Blvd, Brisbane, CA 94005 USA
[3] Blackhawk Plast Surg & MedSpa, Danville, CA USA
[4] Florida Atlantic Univ, Dermatol, Schmidt Coll Med, Boca Raton, FL 33431 USA
关键词
acne vulgaris; Diode laser; Photothermolysis; dermatology; Sebaceous glands; RESISTANCE;
D O I
10.1111/jocd.15602
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
BackgroundSelective photothermolysis on sebaceous glands is an effective method for treating acne vulgaris (AV); however, safety, efficacy, and discomfort hinder its utilization in clinical settings. AimsThe primary objective is to evaluate the safety and efficacy of a novel 1726nm laser with contact cooling to treat AV. MethodsSeventeen patients aged 18 to 36 were enrolled and treated in this IRB-approved, single-center, open-label study. Patients received up to three facial laser sessions up to seven weeks apart. Follow-up visits happened ten days post-session and at the 4 and 12weeks following the final session. The investigator assessed the severity of device-related adverse events (AEs). Investigator Global Assessment (IGA) and inflammatory lesion counts (ILC) were used as metrics to evaluate acne resolution and skin condition enhancement. Patients' perspectives on satisfaction and comfort using this technology were assessed using Subject Experience Questionnaires (SEQ). ResultsSafety assessment showed mild and transient AEs. All subjects tolerated anesthetics-free treatments well, with a mean treatment discomfort score of 4.9 1.5. Compared to baseline, a statistically significant reduction in ILC (p = 0.003) of 52% to 56% is achieved four to twelve weeks following treatment. Long-term follow-ups showed progressive improvement 24months post-treatment with a 97% reduction in ILC. SEQs revealed high subject satisfaction (71%) with psychosocial improvement three months post-treatment. ConclusionThe novel 1726nm laser appears safe and effective for treating mild-to-severe acne. Acne resolution is apparent within the first month and progresses beyond the study duration.
引用
收藏
页码:486 / 496
页数:11
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