Obesity and Dyslipidemia

被引:72
作者
Nussbaumerova, Barbora [1 ]
Rosolova, Hana [1 ]
机构
[1] Chales Univ, Fac Med Pilsen, Med Dept 2, Alej Svobody 76, Plzen 32300, Czech Republic
关键词
Visceral obesity; Dyslipidemia; Metabolic syndrome; Cardiovascular risk; Lifestyle; Hypolipidemic treatment; CONTROLLED-RELEASE PHENTERMINE/TOPIRAMATE; VISCERAL ADIPOSITY INDEX; CARDIOVASCULAR-DISEASE; PHYSICAL-ACTIVITY; CONTROLLED-TRIAL; STATIN THERAPY; LIPID PROFILE; WEIGHT; RISK; CHOLESTEROL;
D O I
10.1007/s11883-023-01167-2
中图分类号
R6 [外科学];
学科分类号
1002 ; 100210 ;
摘要
Purpose of ReviewThis article sumarizes pathopysiological consequencies between obesity and dyslipidemia and aims to bring some practical approach.Recent FindingsDyslipidemia is often present in individuals with obesity and simultaneusly, many obese individuals have lipid metabolism disorders. Especially the abdominal obesity increases the cardiometabolic risk because of the presence of atherogenic dyslipidemia while the total low density lipoprotein cholesterol (LDL-C) may be normal. LDL-C is the primary goal in dyslipidemia treatment. Apoliprotein B (Apo B) and non - high density lipoprotein cholesterol (non-HDL-C) should be estimated to precise the cardiovascular risk and represents the secondary goal in treatment. Weight loss either with diet or antiobestic medication induces the decrease in triglycerides (TG) and LDL-C and the increase in HDL-C. Composition of nutrients, esp. fatty acids, influences lipid levels. Bariatric surgery is efficient in weight loss and has a significant effect on serum lipids.SummaryDyslipidemia and obesity present common diseases that must be managed to decrease the cardiovascular risk and the risk of obesity-related complications.
引用
收藏
页码:947 / 955
页数:9
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