Pulmonary Cryptococcosis Complicating Severe Coronavirus Infectious Disease 2019 A Case Report and Review of the Literature

Many case reports have detailed fungal infections associated with coronavirus infectious disease-2019 (COVID-19); however, few reports have described cryptococcal infection in individuals with COVID-19. The use of immunomodulatory medications as part of COVID-19 treatment including corticosteroids and tocilizumab increases the risk of invasive fungal infections. Herein we review the existing reports of cryptococcal infection in the setting of COVID-19 and present a case of a previously immunocompetent patient who was diagnosed with pulmonary cryptococcosis after being treated with prolonged corticosteroids for severe COVID-19 and organizing pneumonia.