Molecular imprinted polymers: important advances in biochemistry, biomedical and biotechnology

被引:7
作者
Acet, Burcu Onal [1 ]
Inanan, Tulden [2 ]
Salieva, Kalipa [3 ]
Borkoev, Bakyt [3 ]
Odabasi, Mehmet [1 ]
Acet, Omur [4 ]
机构
[1] Aksaray Univ, Fac Arts & Sci, Chem Dept, Aksaray, Turkiye
[2] Aksaray Univ, Tech Sci Vocat Sch, Aksaray, Turkiye
[3] Kyrgyz Turkish Manas Univ, Fac Engn, Chem Engn, Bishkek, Kyrgyzstan
[4] Tarsus Univ, Vocat Sch Hlth Sci, Pharm Serv Program, Tarsus, Turkiye
关键词
Molecular imprinted polymers; Biochemistry; Biomedical; Biotechnology; TARGETED DRUG-DELIVERY; BOVINE SERUM-ALBUMIN; SUSTAINED-RELEASE; RECOGNITION; NANOPARTICLES; BIOCOMPATIBILITY; GRAPHENE; DEVICES;
D O I
10.1007/s00289-024-05238-5
中图分类号
O63 [高分子化学(高聚物)];
学科分类号
070305 ; 080501 ; 081704 ;
摘要
Molecularly imprinted polymers (MIPs) are handmade receptors that mimic the binding of natural antibodies. In other words, MIPs can selectively bind to the target molecule and qualify as bio-inspired synthetic materials. Today, MIPs are used extensively and are being developed further for biological applications. High cost and time consuming techniques are compelling factors for the field of biochemistry, biomedicine and biotechnology (3B), and there is an urgent need for an alternative, cheap, easy to produce, fast and effective method in these fields. MIPs stand out as a promising way for this purpose. MIPs have superiorities such as specific recognition specificity, excellent sensitivity selectivity and reusability. From this point of view, we examined MIP-related drug delivery studies, cell recognition, enzyme applications, in vivo applications, and applications for some important biomolecules. The aim of this review is to compile the utilizations, advantages, important developments and future expectations of MIPs for the fields of 3B.
引用
收藏
页码:10439 / 10459
页数:21
相关论文
共 97 条
  • [1] A rational approach for 3D recognition and removal of L-asparagine via molecularly imprinted membranes
    Acet, Omur
    Noma, Samir Abbas Ali
    Acet, Burcu Onal
    Dikici, Emrah
    Osman, Bilgen
    Odabasi, Mehmet
    [J]. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2023, 226
  • [2] Detection of N-hexanoyl-L-homoserine lactone via MIP-based QCM sensor: preparation and characterization
    Acet, Omur
    Odabasi, Mehmet
    [J]. POLYMER BULLETIN, 2023, 80 (06) : 6657 - 6674
  • [3] Spatially functionalized polymer surfaces produced via cell-mediated lithography
    Alexander, C
    Vulfson, EN
    [J]. ADVANCED MATERIALS, 1997, 9 (09) : 751 - 755
  • [4] Molecularly imprinted polymers for drug delivery
    Alvarez-Lorenzo, C
    Concheiro, A
    [J]. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2004, 804 (01): : 231 - 245
  • [5] Andrushko V, 2013, STEREOSELECTIVE SYNT, P1
  • [6] Synthesis, characterization and in vivo drug delivery study of a biodegradable nano-structured molecularly imprinted polymer based on cross-linker of fructose
    Asadi, Ebadullah
    Abdouss, Majid
    Leblanc, Roger M.
    Ezzati, Noushin
    Wilson, James N.
    Kordestani, Davood
    [J]. POLYMER, 2016, 97 : 226 - 237
  • [7] Universal method for synthesis of artificial gel antibodies by the imprinting approach combined with a unique electrophoresis technique for detection of minute structural differences of proteins, viruses, and cells (bacteria).: III:: Gel antibodies against cells (bacteria)
    Bacskay, Ivett
    Takatsy, Aniko
    Vegvari, Akos
    Elfwing, Anders
    Balllagi-Pordany, Andras
    Kilar, Ferenc
    Hjerten, Stellan
    [J]. ELECTROPHORESIS, 2006, 27 (23) : 4682 - 4687
  • [8] Molecularly Imprinted Carriers for Diagnostics and Therapy-A Critical Appraisal
    Balcer, Emilia
    Sobiech, Monika
    Lulinski, Piotr
    [J]. PHARMACEUTICS, 2023, 15 (06)
  • [9] In Vivo Applications of Molecularly Imprinted Polymers for Drug Delivery: A Pharmaceutical Perspective
    Baraian, Alexandra-Iulia
    Iacob, Bogdan-Cezar
    Bodoki, Andreea Elena
    Bodoki, Ede
    [J]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 23 (22)
  • [10] Batista A.D., 2021, Med. Dev. Sensors, V4, DOI [10.1002/mds3.10166, DOI 10.1002/MDS3.10166]