Stereotactic Awake Basal Ganglia Electrophysiological Recording and Stimulation (SABERS): A Novel Staged Procedure for Personalized Targeting of Deep Brain Stimulation in Pediatric Movement and Neuropsychiatric Disorders

被引:0
作者
Liker, Mark A. [1 ,2 ]
Sanger, Terence D. [3 ,4 ,5 ,6 ,11 ]
MacLean, Jennifer A. [4 ,6 ]
Nataraj, Jaya [3 ]
Arguelles, Enrique [7 ]
Krieger, Mark [2 ,8 ]
Robison, Aaron [9 ]
Olaya, Joffre [1 ,10 ]
机构
[1] Childrens Hosp Orange Cty, Divison Neurosurg, Orange, CA USA
[2] Univ Southern Calif, Keck Sch Med, Dept Neurol Surg, Los Angeles, CA USA
[3] Univ Calif Irvine, Samueli Sch Engn, Irvine, CA USA
[4] Childrens Hosp Orange Cty, Res Inst, Orange, CA 92668 USA
[5] Univ Calif Irvine, Sch Med, Dept Pediat, Irvine, CA USA
[6] Childrens Hosp Orange Cty, Dept Neurol, Orange, CA USA
[7] Univ Southern Calif, Dept Biomed Engn, Los Angeles, CA USA
[8] Childrens Hosp Los Angeles, Dept Surg, Los Angeles, CA USA
[9] Loma Linda Univ, Sch Med, Dept Neurosurg, Loma Linda, CA USA
[10] Univ Calif Irvine, Sch Med, Dept Neurol Surg, Irvine, CA USA
[11] Childrens Hosp Orange Cty, Dept Neurol, 1201 W La Veta St, Orange, CA 92868 USA
关键词
neuromodulation; dystonia; deep brain stimulation; Tourette syndrome; pediatric; movement disorders; RATING-SCALE; DYSTONIA; RELIABILITY;
D O I
10.1177/08830738231224057
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Selection of targets for deep brain stimulation (DBS) has been based on clinical experience, but inconsistent and unpredictable outcomes have limited its use in patients with heterogeneous or rare disorders. In this large case series, a novel staged procedure for neurophysiological assessment from 8 to 12 temporary depth electrodes is used to select targets for neuromodulation that are tailored to each patient's functional needs. Thirty children and young adults underwent deep brain stimulation target evaluation with the new procedure: Stereotactic Awake Basal ganglia Electrophysiological Recording and Stimulation (SABERS). Testing is performed in an inpatient neuromodulation monitoring unit over 5-7 days, and results guide the decision to proceed and the choice of targets for permanent deep brain stimulation implantation. Results were evaluated 3-6 months postoperatively with the Burke-Fahn-Marsden Dystonia Rating Scale and the Barry-Albright Dystonia Scale. Stereotactic Awake Basal ganglia Electrophysiological Recording and Stimulation testing allowed modulation to be tailored to specific neurologic deficits in a heterogeneous population, including subjects with primary dystonia, secondary dystonia, and Tourette syndrome. All but one subject were implanted with 4 permanent deep brain stimulation leads. Results showed significant improvement on both scales at postoperative follow-up. No significant adverse events occurred. Use of the Stereotactic Awake Basal ganglia Electrophysiological Recording and Stimulation protocol with evaluation in the neuromodulation monitoring unit is feasible and results in significant patient benefit compared with previously published results in these populations. This new technique supports a significant expansion of functional neurosurgery to predict effective stimulation targets in a wide range of disorders of brain function, including those for which the optimal target is not yet known.
引用
收藏
页码:33 / 44
页数:12
相关论文
共 38 条
  • [1] Phenomenology and classification of dystonia: A consensus update
    Albanese, Alberto
    Bhatia, Kailash
    Bressman, Susan B.
    DeLong, Mahlon R.
    Fahn, Stanley
    Fung, Victor S. C.
    Hallett, Mark
    Jankovic, Joseph
    Jinnah, Hyder A.
    Klein, Christine
    Lang, Anthony E.
    Mink, Jonathan W.
    Teller, Jan K.
    [J]. MOVEMENT DISORDERS, 2013, 28 (07) : 863 - 873
  • [2] Which patients with dystonia benefit from deep brain stimulation? A metaregression of individual patient outcomes
    Andrews, Caroline
    Aviles-Olmos, Iciar
    Hariz, Marwan
    Foltynie, Thomas
    [J]. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2010, 81 (12) : 1383 - 1389
  • [3] [Anonymous], 2022, Linear mixed-effects models using "Eigen"and S4 R package lme4 version 1.1-28
  • [4] What parents think and feel about deep brain stimulation in paediatric secondary dystonia including cerebral palsy: A qualitative study of parental decision-making
    Austin, Altana
    Lin, Jean-Pierre
    Selway, Richard
    Ashkan, Keyoumars
    Owen, Tamsin
    [J]. EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY, 2017, 21 (01) : 185 - 192
  • [5] Pallidal Deep Brain Stimulation in a 5-Year-Old Child with Dystonic Storm: Case Report
    Aydin, Sabri
    Abuzayed, Bashar
    Uysal, Serap
    Unver, Olcay
    Uzan, Mustafa
    Mengi, Murat
    Kizilkilic, Osman
    Hanci, Murat
    [J]. TURKISH NEUROSURGERY, 2013, 23 (01) : 125 - 128
  • [6] Reliability and responsiveness of the Barry-Albright dystonia scale
    Barry, MJ
    VanSwearingen, JM
    Albright, AL
    [J]. DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY, 1999, 41 (06) : 404 - 411
  • [7] Current and emerging strategies for treatment of childhood dystonia
    Bertucco, Matteo
    Sanger, Terence D.
    [J]. JOURNAL OF HAND THERAPY, 2015, 28 (02) : 185 - 194
  • [8] Closed Loop Deep Brain Stimulation for PTSD, Addiction, and Disorders of Affective Facial Interpretation: Review and Discussion of Potential Biomarkers and Stimulation Paradigms
    Bina, Robert W.
    Langevin, Jean-Phillipe
    [J]. FRONTIERS IN NEUROSCIENCE, 2018, 12
  • [9] Deep Brain Stimulation in the Treatment of Obsessive-Compulsive Disorder
    Blomstedt, Patric
    Sjoberg, Rickard L.
    Hansson, Maja
    Bodlund, Owe
    Hariz, Marwan I.
    [J]. WORLD NEUROSURGERY, 2013, 80 (06) : E245 - E253
  • [10] Pharmacological and neurosurgical interventions for individuals with cerebral palsy and dystonia: a systematic review update and meta-analysis
    Bohn, Emma
    Goren, Katherine
    Switzer, Lauren
    Falck-Ytter, Yngve
    Fehlings, Darcy
    [J]. DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY, 2021, 63 (09) : 1038 - +