Tuberculosis: The tug of war between pathogen and inflammasome

被引：1
|
作者：
Van Hauwermeiren, Filip [1 ]
Lamkanfi, Mohamed [2 ]
机构：
[1] Pharmaceut Co Johnson & Johnson, Janssen Immunosciences World Dis Accelerator, B-2340 Beerse, Belgium
[2] Univ Ghent, Dept Internal Med & Paediat, Lab Med Immunol, B-9000 Ghent, Belgium
来源：
CURRENT BIOLOGY | 2023年 / 33卷 / 01期
关键词：
GASDERMIN D; CELL-DEATH; INTERLEUKIN-1; VIRULENCE; DEFENSE; IFN;
D O I：
10.1016/j.cub.2022.11.025
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A new study reveals how Mycobacterium tuberculosis evades anti-bacterial immunity by modifying the plasma membrane phospholipid composition of infected macrophages, thereby blocking the host's pyroptosis response and supporting chronic infection.
引用
收藏
页码：R33 / R36
页数：4
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