The Recent Management of Vestibular Schwannoma Radiotherapy: A Narrative Review of the Literature

被引:2
作者
Brun, Lucie [1 ]
Mom, Thierry [2 ]
Guillemin, Florent [3 ]
Puechmaille, Mathilde [2 ]
Khalil, Toufic [4 ]
Biau, Julian [3 ,5 ]
机构
[1] Univ Hosp Lyon, Dept Radiat Oncol, F-69002 Lyon, France
[2] Univ Hosp Clermont Ferrand, Dept Otolaryngol Head & Neck Surg, F-63000 Clermont Ferrand, France
[3] Jean Perrin Ctr, Dept Radiat Oncol, 51 Rue Montalembert, F-63100 Clermont Ferrand, France
[4] Univ Hosp Clermont Ferrand, Dept Neurol Surg, F-63000 Clermont Ferrand, France
[5] Univ Clermont Auvergne, INSERM, U1240 IMoST, F-63011 Clermont Ferrand, France
关键词
radiotherapy; radiosurgery; vestibular schwannoma; FRACTIONATED STEREOTACTIC RADIOTHERAPY; GAMMA-KNIFE RADIOSURGERY; HEARING PRESERVATION; RADIATION-THERAPY; ACOUSTIC NEUROMAS; TUMOR-CONTROL; MALIGNANT-TRANSFORMATION; MICROSURGICAL RESECTION; OUTCOMES; EXPANSION;
D O I
10.3390/jcm13061611
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background: Radiotherapy (RT) plays an important role in the therapeutic management of vestibular schwannoma (VS). Fractionated stereotactic radiotherapy (FSRT) or radiosurgery (SRS) are the two modalities available. The purpose of this article is to review the results of VS RT studies carried out over the last ten years. Materials and Methods: A literature search was performed with PubMed and Medline by using the words vestibular schwannoma, acoustic neuroma, radiotherapy, and radiosurgery. Results: In small (<3 cm) VS, SRS offers a local control rate of >90%, which seems similar to microsurgery, with a favorable tolerance profile. Hypofractionated FSRT (three to five fractions) is a relatively recent modality and has shown similar outcomes to normofractionated FSRT. Hearing preservation may highly differ between studies, but it is around 65% at 5 years. Conclusions: SRS and FRST are non-invasive treatment options for VS. SRS is often preferred for small lesions less than 3 cm, and FSRT for larger lesions. However, no randomized study has compared these modalities.
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页数:14
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