KRASG12C exhibits allele-specific biology in pancreatic cancer and targeting CD24 sensitizes KRASG12C-driven tumors to sotorasib treatment

被引：0
作者：
Wei, Yongkun
Liu, Minghui
Nguyen, Phuoc T.
Pan, Dean N.
Yao, Wantong
Ying, Haoqiang
机构：
来源：
CANCER RESEARCH | 2024年 / 84卷 / 02期
关键词：
D O I：
10.1158/1538-7445.PANCA2023-C097
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
C097
引用
收藏
页数：2
相关论文
共 50 条
  • [1] Sotorasib in KRASG12C mutated lung cancer
    Olivier, Timothee
    Prasad, Vinay
    LANCET, 2024, 403 (10422)
  • [2] KRASG12C Inhibition with Sotorasib in Advanced Solid Tumors
    Hong, David S.
    Fakih, Marwan G.
    Strickler, John H.
    Desai, Jayesh
    Durm, Gregory A.
    Shapiro, Geoffrey I.
    Falchook, Gerald S.
    Price, Timothy J.
    Sacher, Adrian
    Denlinger, Crystal S.
    Bang, Yung-Jue
    Dy, Grace K.
    Krauss, John C.
    Kuboki, Yasutoshi
    Kuo, James C.
    Coveler, Andrew L.
    Park, Keunchil
    Kim, Tae Won
    Barlesi, Fabrice
    Munster, Pamela N.
    Ramalingam, Suresh S.
    Burns, Timothy F.
    Meric-Bernstam, Funda
    Henary, Haby
    Ngang, Jude
    Ngarmchamnanrith, Gataree
    Kim, June
    Houk, Brett E.
    Canon, Jude
    Lipford, J. Russell
    Friberg, Gregory
    Lito, Piro
    Govindan, Ramaswamy
    Li, Bob T.
    NEW ENGLAND JOURNAL OF MEDICINE, 2020, 383 (13) : 1207 - 1217
  • [3] Sotorasib/SHP2 inhibitors combo, KRASG12C(ON)I and RASMULTI(ON)I effectively target KRASG12C tumors developing secondary resistance to Sotorasib via KRASG12C amplification
    Solanki, Hitendra S.
    Imbody, Denis
    Desai, Bina
    Kato, Ryoji
    Stewart, Paul A.
    Stern, Yaakov
    Majumder, Anurima
    Bridenstine, Liznair
    Sarca, Bhaswati
    Miroshnychenko, Dada
    Aronchik, Ida
    Marusyk, Andriy
    Haura, Eric B.
    MOLECULAR CANCER THERAPEUTICS, 2023, 22 (12)
  • [4] Sotorasib shows clinical benefits in KRASG12C colorectal cancer
    Di Lellis, Maddalena Angela
    ZEITSCHRIFT FUR GASTROENTEROLOGIE, 2022, 60 (05):
  • [5] Sotorasib in KRASG12C mutated lung cancer - Authors' reply
    Paz-Ares, Luis
    Mehta, Bhakti
    Wang, Yang
    Obiozor, Cynthia
    Waterhouse, David
    de Langen, Adrianus Johannes
    LANCET, 2024, 403 (10422) : 145 - 146
  • [6] Cooperative anti-tumor effects of combined inhibition of KRASG12C plus autophagy in preclinical models of KRASG12C-driven lung cancer
    Ghazi, Phaedra C.
    Kinsey, Conan
    Bogdan, Madhumita
    Smith, Bryan D.
    Flynn, Daniel L.
    McMahon, Martin
    MOLECULAR CANCER RESEARCH, 2023, 21 (05)
  • [7] Adaptive Mechanisms and Synergistic Combinations to Overcome Sotorasib Resistance in KRASG12C-Driven NSCLC
    Arantes Megid, R.
    Gomes Ribeiro, G.
    Natalia Faria Gomes, I.
    Carolina Laus, A.
    Ferro Leal, L.
    Sussuchi Da Silva, L.
    Bakr Ariwoola, A.
    Mourao Dias, J.
    Manuel Reis, R.
    Jose Da Silva Oliveira, R.
    EUROPEAN JOURNAL OF CANCER, 2024, 211 : S143 - S144
  • [8] Sotorasib Tackles KRASG12C-Mutated Pancreatic Cancer
    Osterweil, Neil
    CANCER DISCOVERY, 2022, 12 (04) : 878 - 879
  • [9] Sotorasib: a KRASG12C inhibitor for non-small cell lung cancer
    Ganguly, Arghya
    Yoo, Euna
    TRENDS IN PHARMACOLOGICAL SCIENCES, 2022, 43 (06) : 536 - 537
  • [10] Targeting KRASG12C in colorectal cancer: the beginning of a new era
    Ciardiello, D.
    Maiorano, B. A.
    Martinelli, E.
    ESMO OPEN, 2023, 8 (01)
12345