Super-resolution imaging of mitochondrial cristae using a more hydrophobic far-red Si-rhodamine probe

被引：6
作者：
Sun, Jing [1 ]
Ge, Xichuan [1 ]
Jin, Boya [2 ,3 ]
Li, Shiyi [1 ]
Hou, Yiwei [2 ,3 ]
Zhong, Suyi [2 ,3 ]
Yang, Zikang [1 ]
Xi, Peng [2 ,3 ]
Li, Meiqi [4 ]
Gao, Baoxiang [1 ]
机构：
[1] Hebei Univ, Coll Chem & Mat Sci, Key Lab Analyt Sci & Technol Hebei Prov, Baoding 071002, Hebei, Peoples R China
[2] Peking Univ, Coll Future Technol, Dept Biomed Engn, Beijing 100871, Peoples R China
[3] Peking Univ, Natl Biomed Imaging Ctr, Beijing 100871, Peoples R China
[4] Peking Univ, Sch Life Sci, Beijing 100871, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2023年 / 59卷 / 87期
基金：
中国国家自然科学基金;
关键词：
FLUORESCENT-PROBES; DEGRADATION; EMISSION;
D O I：
10.1039/d3cc04696f
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Mitochondrial probe SiRPFA was synthesized by attaching a long perfluoroalkyl chain on Si-rhodamine cationic dye. High lipophilicity endowed SiRPFA with mitochondrial membrane potential independent properties. Under stimulated emission depletion microscopy, SiRPFA clearly revealed changes in mitochondrial cristae morphology during autophagy induced by starvation or apoptosis.
引用
收藏
页码：13038 / 13041
页数：4
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