Experimental investigation of rheological properties of niosomal dispersions

被引:0
|
作者
Diskaeva, Elena I. [1 ]
Vecher, Olga V. [1 ]
Diskaeva, Elena N. [2 ]
Bazikov, Igor A. [3 ]
Elbekyan, Karine S. [4 ]
机构
[1] Stavropol State Med Univ, Dept Phys & Math, Mira 310, Stavropol 355017, Russia
[2] MIREA Russian Technol Univ, Branch Fed State Budget Educ Inst Higher Educ, Kulakov Ave 8, Stavropol 355035, Russia
[3] Stavropol State Med Univ, Dept Microbiol, Mira 310, Stavropol 355017, Russia
[4] Stavropol State Med Univ, Dept Gen & Biol Chem, Mira 310, Stavropol 355017, Russia
来源
关键词
nonionic surfactant vesicles; rheological properties; niosomal dispersion; DRUG-DELIVERY; PARTICLE-SIZE; IN-VITRO; CARRIERS;
D O I
10.17586/2220-8054-2023-14-2-195-201
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
In this work, the rheological properties of niosomal dispersions of various concentrations in the temperature range of 30 - 60 degrees C is investigated. The viscosity coefficient and the values of the activation energy were determined experimentally. It is found that the flow of niosomal dispersions exhibits the properties of Newtonian fluids in the studied range of temperatures and shear rates. Conditions were determined for obtaining stable homogeneous niosomal dispersions with an average vesicle size of 80 - 150 nm.
引用
收藏
页码:195 / 201
页数:7
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